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临床试验/NCT06497569
NCT06497569
招募中
不适用

Support Through Remote Observation and Nutrition Guidance Program for Individuals With Gastroesophageal Cancer (STRONG-GEC)

H. Lee Moffitt Cancer Center and Research Institute2 个研究点 分布在 1 个国家目标入组 80 人2024年7月26日

概览

阶段
不适用
干预措施
Dietitian Consultation
疾病 / 适应症
GastroEsophageal Cancer
发起方
H. Lee Moffitt Cancer Center and Research Institute
入组人数
80
试验地点
2
主要终点
Recruitment Rate- Feasibility
状态
招募中
最后更新
3个月前

概览

简要总结

The purpose of this study is to determine how the STRONG intervention compares with usual care for reducing malnutrition among gastroesophageal cancer patients.

注册库
clinicaltrials.gov
开始日期
2024年7月26日
结束日期
2027年6月1日
最后更新
3个月前
研究类型
Interventional
研究设计
Parallel
性别
All

研究者

入排标准

入选标准

  • Participants must be 18 years of age or older
  • Participants must have locally advanced or metastatic gastroesophageal cancer (GEC)
  • Participants must plan to initiate chemotherapy and/or radiation therapy with a plan to have surgery or definitive treatment follow up at Moffitt
  • Participants must be able to speak and read Spanish and/or English
  • Participants must be able to provide informed consent

排除标准

  • Participants have a documented or observable psychiatric or neurological disorder that would interfere with study participation (e.g. severe dementia)
  • Use of feeding tubes at the time of study enrollment

研究组 & 干预措施

STRONG Intervention

Participants will receive an initial consultation and biweekly follow-up visits with a study dietitian for 90 days. During the follow-up visits, the study dietitian will review the dietary plan and goals, review the dietary food log, and discuss any challenges with dietary intake and recommendations for improving dietary intake. Participants will keep a daily diary of food intake with a Fitbit smartphone app and a Fitbit wearable device for 90 days, complete 6 questionnaires, and have the option to participate in a voluntary interview about the intervention.

干预措施: Dietitian Consultation

STRONG Intervention

Participants will receive an initial consultation and biweekly follow-up visits with a study dietitian for 90 days. During the follow-up visits, the study dietitian will review the dietary plan and goals, review the dietary food log, and discuss any challenges with dietary intake and recommendations for improving dietary intake. Participants will keep a daily diary of food intake with a Fitbit smartphone app and a Fitbit wearable device for 90 days, complete 6 questionnaires, and have the option to participate in a voluntary interview about the intervention.

干预措施: Survey

STRONG Intervention

Participants will receive an initial consultation and biweekly follow-up visits with a study dietitian for 90 days. During the follow-up visits, the study dietitian will review the dietary plan and goals, review the dietary food log, and discuss any challenges with dietary intake and recommendations for improving dietary intake. Participants will keep a daily diary of food intake with a Fitbit smartphone app and a Fitbit wearable device for 90 days, complete 6 questionnaires, and have the option to participate in a voluntary interview about the intervention.

干预措施: Fitbit Data Collection

STRONG Intervention

Participants will receive an initial consultation and biweekly follow-up visits with a study dietitian for 90 days. During the follow-up visits, the study dietitian will review the dietary plan and goals, review the dietary food log, and discuss any challenges with dietary intake and recommendations for improving dietary intake. Participants will keep a daily diary of food intake with a Fitbit smartphone app and a Fitbit wearable device for 90 days, complete 6 questionnaires, and have the option to participate in a voluntary interview about the intervention.

干预措施: Social Determinants of Health Survey (SDOH)

Usual Care Intervention

Participants will be referred to a study dietitian based on their standard-care clinician's discretion, complete 6 questionnaires, and have the option to participate in a voluntary interview about the intervention.

干预措施: Dietitian Consultation

Usual Care Intervention

Participants will be referred to a study dietitian based on their standard-care clinician's discretion, complete 6 questionnaires, and have the option to participate in a voluntary interview about the intervention.

干预措施: Survey

Usual Care Intervention

Participants will be referred to a study dietitian based on their standard-care clinician's discretion, complete 6 questionnaires, and have the option to participate in a voluntary interview about the intervention.

干预措施: Referral to Dietitian

结局指标

主要结局

Recruitment Rate- Feasibility

时间窗: Up to 48 Months

The Study will be deemed feasible ≥ 50% of eligible patients are enrolled.

Patient-reported outcome completion-Feasibility

时间窗: Up to 6 Months

The Study will be deemed feasible if ≥ 70% of participants enrolled submit 4 of the 6 study assessments.

Retention Rate- Feasibility

时间窗: Up to 90 Days

The Study will be deemed feasible if ≥ 70% of participants enrolled at baseline are retained at the end of the intervention period.

Patient Rating of MyPlate app-Feasibility

时间窗: Up to 6 Months

The Study will be deemed feasible if ≥ 70% of participants rate the MyPlate app as east-to use utilizing a validated usability scale (score ≥ 60).

Food Log Data Collection-Feasibility

时间窗: Up to 6 Months

The study will be deemed feasible if ≥ 70% of participants enrolled log food for greater than 80% of study days (72 out of 90).

Participant Satisfaction- Acceptability

时间窗: Up to 6 Months

Patient satisfaction with the intervention will be deemed acceptable if ≥ 70% of participants rate the intervention as satisfactory utilizing a validated 4 item scale (score range 0-20). A cutoff score of ≥ 12 based on prior studies to define intervention acceptability will be used.

Adherence to Dietitian Visits- Feasibility

时间窗: Up to 6 Months

The Study will be deemed feasible if ≥ 70% of participants enrolled attend 4 out of 6 dietitian visits.

Fidelity to Study Protocol- Feasibility

时间窗: Up to 6 Months

The Study will be deemed feasible if 20% of randomly audited dietitian visits have documented PG-SGA and calorie and protein goals

次要结局

  • Malnutrition - Low Skeletal Muscle Mass(Baseline, 3 Months, 6 Months)
  • Malnutrition - Low BMI(Baseline, 3 Months, 6 Months)
  • Malnutrition -Nutritional Status(Baseline, 3 Months, 6 Months)
  • Treatment Adherence(Baseline, 3 Months, 6 Months)
  • Malnutrition-Significant weight loss(Baseline, 3 Months, 6 Months)
  • Quality of Life Questionnaires(Baseline, 3 Months, 6 Months)
  • Progression Free Survival (PFS)(Up to 48 Months)

研究点 (2)

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