A study to see the additive epidural analgesic effect of two drugs dexmedetomidine & fentanyl
Phase 1/2
Not yet recruiting
- Conditions
- Central pain syndrome,
- Registration Number
- CTRI/2020/05/025233
- Lead Sponsor
- Ptjnm medical college
- Brief Summary
A comparative interventionals study between fentanyl & dexmedetomidine as adjuvant (enhancement of duration of sensory block or analgesia with lower degree of motor block) epidural Ropivacainefor post operative analgesia in spine surgery (Lumbar laminectomy)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Patients undergoing lower thoracic (below T8)& lumbosacral spine fixation.
Exclusion Criteria
- 1.Refuse to participate, 2.chronic pain syndrome, 3.
- cardiac diseases,4.hematological disease, 5.psychiatric disease,6.allergy to local anaesthetic, 7.upper thoracic & 8.cervical spine surgery,9.tubercular spine.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Analgesia using VISUAL ANALOG SCORE. 1year
- Secondary Outcome Measures
Name Time Method Patients satisfaction Ramsay sedation score
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms by which dexmedetomidine enhances epidural ropivacaine analgesia in lumbar laminectomy patients?
How does the combination of fentanyl and dexmedetomidine compare to standard-of-care analgesics in postoperative spinal surgery pain management?
Which biomarkers could predict differential response to fentanyl versus dexmedetomidine as adjuvants in central pain syndrome patients?
What are the potential adverse events associated with using dexmedetomidine as an epidural adjuvant in spinal surgery?
How do alpha-2 adrenergic agonists like dexmedetomidine compare to opioid analgesics in postoperative analgesia for central pain syndrome?
Trial Locations
- Locations (1)
PTJNM Medical college
🇮🇳Raipur, CHHATTISGARH, India
PTJNM Medical college🇮🇳Raipur, CHHATTISGARH, IndiaDRCPBHAGATPrincipal investigator9575799345cpbhagat@gmail.com