A pilot randomised controlled trial to examine the efficacy and optimal dose of acetic acid to treat colonised burns wounds

niversity Hospitals Birmingham NHS Foundation Trust0 个研究点目标入组 22 人开始时间: 2018年1月29日最近更新: 2023年10月9日

试验速览

2023 Protocol article in https://pubmed.ncbi.nlm.nih.gov/37748846/ (added 26/09/2023)

•Current inclusion criteria as of 27/11/2020:
•1. At least one =1% TBSA burn injury prior to enrolment
•2. Burn wound colonised with a specifically identifiable bacterium
•3. Aged =16 years old
•4. Anticipated to remain as inpatient for the study duration i.e. 3 days
•Previous inclusion criteria as of 03/08/2018:
•1. Patient to have a =1% TBSA burn injury/ies prior to enrolment
•2. Burn wound colonised with a specifically identifiable bacteria
•3. Patients aged =18 years old
•4. Patients who are anticipated to remain as inpatients for the study duration i.e. 5 days
•Previous inclusion criteria:
•1. Patient to have a 1 - <10 % TBSA burn injury prior to enrolment
•2. Burn wound colonised with a specifically identifiable bacteria
•3. Patients aged =18 years old
•4. Patients who are anticipated to remain as inpatients for the study duration i.e. 5 day

•Current inclusion criteria as of 27/11/2020:
•1. Burns solely to the face and/or genital area
•2. Patients who have received acetic acid as part of standard therapy upon admission to inpatients for this burn injury
•3. Patients deemed unsuitable to enter trial in the opinion of the investigator
•Previous exclusion criteria as of 03/08/2018:
•1. Patients who lack capacity to give informed consent (NB: translation services will be available for non-English speaking patients)
•2. Patients who are on antibiotics for cellulitis
•3. Patients with burns solely to the face and/or genital area
•4. Patients who have received acetic acid as part of standard therapy upon admission to inpatients for this burn injury
•5. Patients deemed unsuitable to enter trial in the opinion of the investigator
•Previous exclusion criteria:
•1. Patients who lack capacity to give informed consent (NB: translation services will be available for non-English speaking patients)
•2. Patients who are receiving systemic antibiotics
•3. Patients with burns solely to the face and/or genital area
•4. Patients who have received acetic acid as part of standard therapy upon admission to inpatients for this burn injury
•5. Patients deemed unsuitable to enter trial in the opinion of the investigator

发起方

niversity Hospitals Birmingham NHS Foundation Trust