Analysis of inflammatory processes in septic patients: inflammatory mediators, immune response and predisposing factors and their correlation with clinical severity.
Suspended
- Conditions
- SepsisA41Other sepsis
- Registration Number
- DRKS00014588
- Lead Sponsor
- niversitätsklinikum Hamburg-EppendorfKlinik für Intensivmedizin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Suspended
- Sex
- All
- Target Recruitment
- 290
Inclusion Criteria
Patients in an intensive care unit suspected or diagnosed with sepsis according to the Sepsis 3 Definition
Exclusion Criteria
Cardiogenic shock, pregnancy or lactation, lack of consent, moribund state
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum and plasma levels of various cytokines / chemokines including differentiated analysis of immune cells as well as mRNA and DNA, which are subject to regulation at expression level (mRNA / DNA).<br>Explicit, there is no analysis of the genome or chromosomal changes.<br>
- Secondary Outcome Measures
Name Time Method Severity of sepsis, 28d-mortality and mortality in intensive care; also clinical parameters such as ventilation days and need for dialysis