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Post-Operative Analgesic Effect of Tramadol and Nalbuphine in Smoker and Non-Smoker Patients in LC

Active, not recruiting
Conditions
Laparocele
Registration Number
NCT07049380
Lead Sponsor
Superior University
Brief Summary

This study aims to compare pain severity and analgesic requirements between smokers and nonsmokers following laparoscopic cholecystectomy, evaluating the efficacy of two analgesics, tramadol and nalbuphine.

Detailed Description

The primary objectives are to estimate pain severity in smokers versus nonsmokers and identify the effect of tramadol and nalbuphine between these groups.A comparative cross-Sectional design will be employed from Allama Iqbal Teaching Hospital, DG Khan, over four months. Participants will be stratified into subgroups receiving either tramadol or nalbuphine.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
132
Inclusion Criteria
  • Both Male and female patients are included.
  • Adults' patients with Greater than 30 years of age
  • Both Smoker and non-Smokers patients are added (Patients who are chain smoker at least 10 cigarettes per day).
Exclusion Criteria
  • Patients are excluded if they have smoking history other than cigarettes smoking like Vapes, Cigar and smokeless tobacco.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Visual Analog Scale (VAS)12 Months

The Visual Analog Scale (VAS) is a tool used to measure pain intensity, mood, or other subjective experiences. It typically involves a 10 cm (100mm) line with descriptive anchors at each end, such as "no pain" and "worst pain imaginable

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Allama Iqbal Teaching hospital

🇵🇰

Dera Ghazi Khan, Punjab, Pakistan

Allama Iqbal Teaching hospital
🇵🇰Dera Ghazi Khan, Punjab, Pakistan
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