Dark Lumen MR colonography vs. Colonoscopy for the detection of colorectal lesions

• Conditions: colorectal carcinoma; large bowel cancer; 10017990; 10017991

• Registration Number: NL-OMON32956
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 110

Inclusion Criteria

-Symptomatic CRC patients ( rectal blood loss, altered bowel habits)
-Patients scheduled to undergo colonoscopy
-Patients who are willing to give informed consent

Exclusion Criteria

-Age of less than 18 years
-patients who were unable to give informed consent
-any suspicion of bowel perforation or pathologic obstruction in subjects* medical history
-contraindications for oral or intravenous administration of contrast agents as used for this examination
-oral or intravenous administration of barium contrast medium within 48 hours prior to MR colonography (barium enema)
-presence of a colostomy after colorectal surgery
-contraindications to undergo MRI (including claustrophobia, metallic implants and pregnancy)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study endpoint is the diagnostic accuracy of MR colonography in<br /><br>detecting patients with colorectal carcinoma (CRC) , clinical relevant polyps<br /><br>(* 10mm) and intermediate polyps (6-9mm). </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoints are evaluation of the per-polyp detection and patient<br /><br>acceptance.</p><br>