Effect of Buspirone added to Typical Antipsychotics on Positive and Negative symptoms in schizophrenia
Phase 3
- Conditions
- Schizophrenia.Schizophrenia
- Registration Number
- IRCT201106026691N1
- Lead Sponsor
- Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Age between 18-65; Diagnosis of Schizophrenia based on DSMIV-TR; Chronic Schizophrenia(over 2 years); Ongoing treatment with Typical Antipsychotics.
Exclusion criteria:Allergic to Buspirone; Any chronic medical problem; Substance dependency; Any other Psychiatric Disorder in Axis I or II; Pregnancy or Breast feeding.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of schizophrenia. Timepoint: Baseline and weeks 2-4-6 after begining of treatment. Method of measurement: Positive and Negative Syndrome Scale(PANSS).
- Secondary Outcome Measures
Name Time Method Headache. Timepoint: Baseline and weeks 2,4,6 after begining of treatment. Method of measurement: Check list of adverse effects.;Nausea. Timepoint: Baseline and weeks 2-4-6 after begining of treatment. Method of measurement: Checklist of adverse effects.;Palpitation. Timepoint: Baseline and weeks 2-4-6 after begining of treatment. Method of measurement: Checklist of adverse effects.