Anomia Treatment Predictors

Not Applicable

Active, not recruiting

• Conditions: Anomia (Word-Finding Impairment); Aphasia

• Registration Number: NCT06619756
• Lead Sponsor: State University of New York at Buffalo

Brief Summary

The goal of this clinical trial is to identify predictors of response to phonological-focused anomia treatment in people with aphasia. The main question it aims to answer is who responds to which type of anomia treatment. Researchers will compare Phonomotor Treatment and Phonological Components Analysis to see which treatment is more beneficial, and for whom. Participants will engage in both treatments over several months.

Detailed Description

Participants will complete screening and characterization testing to determine eligibility for the study. Each treatment will be administered twice a week, for 10-15 sessions. Pre-treatment and post-treatment testing will also occur for each treatment. There will be a period of no treatment in between the first and second treatment blocks.

Study Timeline

• Study Start: 2024-09-18
• Study First Submitted: 2024-09-27
• Study First Submitted QC: 2024-09-27
• Study First Posted: 2024-10-01
• Status Verified: 2024-12
• Last Update Submitted: 2024-12-05
• Last Update Posted: 2024-12-10
• Primary Completion: 2025-10
• Study Completion: 2026-07

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 2

Inclusion Criteria

• Chronic aphasia (6+ months)
• Anomia
• Sufficient auditory comprehension to follow task instructions
• Phonologic impairment

Exclusion Criteria

• Progressive neurological illness or disease, including dementia
• Chronic medical illness that interferes with adherence to testing schedule
• Severe, uncorrected vision or hearing impairment that interferes with task completion
• Moderate-severe apraxia of speech or dysarthria that interferes with task completion

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Naming of Trained Words	Pre-treatment and Immediately post-treatment	Picture naming of trained words

Secondary Outcome Measures

Name	Time	Method
Naming of Untrained Words	Pre-treatment and Immediately post-treatment	Picture naming of untrained words
Standardized Assessment of Phonology in Aphasia (SAPA)	Pre-treatment and Immediately post-treatment	The SAPA assesses phonological processing abilities, including oral reading, rhyme judgments, minimal pair judgments, lexical decision, blending, and parsing.
Philadelphia Naming Test	Pre-treatment and Immediately post-treatment	The short-form of the Philadelphia Naming Test is a picture naming test of items not seen during treatment.

Trial Locations

Locations (1)

UB Audiology and Speech-Language Pathology Clinic; 🇺🇸 Buffalo, New York, United States