Does Patient-Controlled Infraclavicular Perineural Dexmedetomidine Improve Postoperative Analgesia Deadline?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- visual analog scale
研究概览
简要总结
Infraclavicular block is one of the peripheral nerve block used in upper extremity surgery. Adjuvant agents are used in peripheral nerve blocks to increase the duration and block quality. We investigated that the effects of patient-controlled perineural dexmedetomidine application on postoperative analgesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •be undergoing distal upper extremity surgery
- •Be between 18-65 years
- •to agree to participate in research
排除标准
- •allergy to dexmedetomidine
- •AV block or bradycardia
- •being serious cardiac - liver - kidney function disorders
- •Being coagulopathy
- •neuropathy in the upper extremity
- •adrenoceptor agonists or antagonists use
研究组 & 干预措施
perineural bupivacaine
patient-controlled infraclavicular perineural bupivacaine
(1% bupivacaine (marcaine), 5 ml bolus dose, infusion rate of 5 ml / h, lockout time 1 hour)
干预措施: Bupivacaine (Drug)
perineural bupivacaine
patient-controlled infraclavicular perineural bupivacaine
(1% bupivacaine (marcaine), 5 ml bolus dose, infusion rate of 5 ml / h, lockout time 1 hour)
干预措施: Dexmedetomidine (Drug)
perineural dexmedetomidine
patient-controlled infraclavicular perineural dexmedetomidine
(1% bupivacaine + 200 mic / 100cc dexmedetomidine, 5 ml bolus dose, infusion rate of 5 ml / h, lockout time 1 hour)
干预措施: Bupivacaine (Drug)
perineural dexmedetomidine
patient-controlled infraclavicular perineural dexmedetomidine
(1% bupivacaine + 200 mic / 100cc dexmedetomidine, 5 ml bolus dose, infusion rate of 5 ml / h, lockout time 1 hour)
干预措施: Dexmedetomidine (Drug)
结局指标
主要结局
visual analog scale
时间窗: 3 month
Scores range from 0 \[no pain\] to 10 \[worst possible pain
次要结局
- The effect of dexmedetomidine to the Ramsey Sedation Scale(3 month)
- side effects(3 month)
研究者
ILKE KUPELI
Anaesthesiology and reanimation
Cukurova University