Effect of Platelet-Rich Plasma Injection on Rotator Cuff Tear Repair

Phase 1

Recruiting

• Conditions: Rotator cuff tear.; Unspecified rotator cuff tear or rupture, not specified as traumatic; M75.10

• Registration Number: IRCT20240123060779N1
• Lead Sponsor: Islamic Azad University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 27 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Age range: 18 to 80 years old
Initial tear
Traumatic or degenerative tear with less than 50% thickness
Willingness to participate in the study

Exclusion Criteria

Secondary rotator cuff tear due to fracture or dislocation
Presence of dislocation during the study period
Rotator cuff tears that have previously undergone surgical repair or corrective arthroscopy
Diseases associated with upper limb pain such as arthritis, infection, carpal tunnel syndrome, cervical neuropathy
Localized malignancy
Systemic disorders such as uncontrolled diabetes and hypothyroidism, pregnancy, platelet count less than 125,000
Having definitive disability or inability to attend for follow-up after injection

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Determination of rotator cuff tear repair extent based on changes in percentage of tear. Timepoint: Before intervention and at 2 months and 6 months post-initiation of platelet-rich plasma injection. Method of measurement: Ultrasound imaging.;Determination of rotator cuff tear repair extent based on changes in mediolateral tear length. Timepoint: Before intervention and at 2 months and 6 months post-initiation of platelet-rich plasma injection. Method of measurement: Ultrasound imaging.;Determination of rotator cuff tear repair extent based on changes in pain level. Timepoint: Before intervention and at 2 months and 6 months post-initiation of platelet-rich plasma injection. Method of measurement: Ultrasound imaging.;Determination of rotator cuff tear repair extent based on changes in shoulder range of motion. Timepoint: Before intervention and at 2 months and 6 months post-initiation of platelet-rich plasma injection. Method of measurement: Ultrasound imaging.