Prediction of Hip Displacement in Children With Cerebral Palsy Among Patients Participating in the Danish Cerebral Palsy Follow-up Program
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Development of hip displacement or not measured by the Migration Percentage
研究概览
简要总结
Children with cerebral palsy have an increased risk of hip dislocation, which is a painful and severe complication of cerebral palsy. The 20-years evaluation of the Swedish surveillance programme shows that hip dislocation in children with cerebral palsy can be prevented with regular clinical and radiographic examination and early intervention.
We would like to determine the individual risk for hip displacement for Danish children with CP in The Danish Cerebral Palsy Follow-up Program. This could be a valuable clinical tool in deciding on further follow-up and treatment.
详细描述
Migration percentage (MP) which is measured from the pelvis radiograph is commonly used to assess lateral displacement of the femoral head and is being used in the Swedish and in the Danish surveillance programme. Most children with an MP > 40 % need surgery to prevent further displacement and prevent dislocation of the hip. In the Swedish surveillance programme they have developed the Cerebral Palsy Follow-Up Programme (CPUP) hip score as a risk score to determine which children are at high or low risk for hip displacement (MP > 40 %) within five years after first radiographic examination.
The aim of this study is to predict the likelihood that a child with cerebral palsy will develop hip displacement (MI> 40) within three years. The design is a prediction study.
Data will be obtained from the national clinical quality database the Danish Cerebral Palsy Follow-up Program and the Danish National Patient Register.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children with cerebral palsy
- •Gross Motor Function Classification System III to V
- •Migration Percentage < 40 % for both hips at the first pelvic radiographic examination
排除标准
- •Previous femoral osteotomy
- •Previous pelvic osteotomy
- •Previous selective dorsal rhizotomy
- •Intrathecal baclofen pump treatment
- •Children whose diagnosis was not confirmed
- •Children who were no longer followed in the children's ward at the hospital
- •Children who moved out of the area
- •Children who died during the study period
结局指标
主要结局
Development of hip displacement or not measured by the Migration Percentage
时间窗: Follow-up period of three years.
Migration Percentage (MP) is measured from a pelvis radiograph and is used to assess lateral displacement of the femoral head. A MP \< 40 % on either hip is a good outcome, whereas a MP \> 40 % on either hip is a worse outcome.
次要结局
未报告次要终点
研究者
Mette Røn Kristensen
Regional coordinator for CPOP in the capital region of Denmark
Hvidovre University Hospital