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临床试验/NCT06811350
NCT06811350进行中(未招募)不适用

Quality Improvement Initiative for Enhancing Early Mobilization in Intracerebral Hemorrhage Patients: Pre-Post Implementation of a Structured Clinical Pathway

National Taiwan University Hospital1 个研究点 分布在 1 个国家目标入组 198 人开始时间: 2024年11月28日最近更新:

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
198
试验地点
1
主要终点
Modified ICU mobility scale

研究概览

简要总结

Primary intracerebral hemorrhage (ICH) is a severe and life-threatening condition with a high mortality rate, reaching up to 50% within the first month. Survivors are often at risk of long-term disability due to the extensive brain damage caused by the hemorrhage. Unlike ischemic stroke patients, ICH patients are typically younger, face longer hospital stays, and are more likely to experience acute complications. Modern treatment approaches have shifted from focusing solely on reducing mortality to minimizing disability and enhancing functional outcomes through early rehabilitation. However, the optimal timing and intensity of early mobilization remain unclear, especially for patients with severe ICH, where medical stability is a major concern. Delays in initiating rehabilitation may limit neuroplasticity and hinder recovery, prompting the need for a structured, multidisciplinary approach to early mobilization in ICH patients.

Objective : This quality improvement (QI) initiative aimed to enhance early mobilization in ICH patients by implementing a structured clinical pathway in an academic stroke center. The goal was to integrate evidence-based early mobilization pathways to improve patient mobility outcomes while ensuring safety through standardized assessments of cardiovascular, respiratory, and neurological stability.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Clinical diagnosis of primary ICH
  • ICH score from 0 to 4
  • Patients In line with the stroke center's standard criteria for early rehabilitation

排除标准

  • Patients with traumatic brain injury, hemorrhagic transformation of ischemic stroke, or hemorrhage related to underlying malignancy
  • Patients placed in palliative care or those who died before initial hospital discharge

结局指标

主要结局

Modified ICU mobility scale

时间窗: through study completion, an average of 12 weeks

The Modified ICU Mobility Scale is used to assess the level of mobility in ICU patients, with scores ranging from 0 to 10. A higher score indicates better mobility, where 0 represents no mobility (lying in bed, passive movements only), and 10 indicates independent ambulation without assistance.

次要结局

  • the time to first mobilization(Through study completion, an average of 12 weeks)
  • National Institutes of Health Stroke Scale (NIHSS) score(through study completion, an average of 12 weeks)
  • Modified Rankin Scale (mRS)(through study completion, an average of 12 weeks)
  • Duration of ICU and hospital stays(Through study completion, an average of 12 weeks)
  • ability to ambulate upon discharge(through study completion, an average of 12 weeks)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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