Transcranial sonography in Parkinson*s Disease and Restless Legs Syndrome - TCS in PD and RLS

Medisch Centrum Haaglanden0 个研究点目标入组 120 人开始时间: 待定最近更新: 2024年7月22日

适应症

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•Inclusion criteria PD patients with RLS
•1.Fulfillment of the United Kingdom PD Society Brain Bank criteria for idiopathic PD.
•2.Definite RLS in which all four revised minimal criteria of RLS are fulfilled based on an personal history taken by a RLS trained investigator/ doctor;Inclusion criteria PD without RLS
•1.Fulfillment of the United Kingdom PD Society Brain Bank criteria for idiopathic PD.
•2.Definite no diagnosis of RLS based on a personal history taken by a RLS trained investigator/ doctor
•3.Age, sex , PD severity (Hoehn & Yahr and total levodopa-equivalent) matched to the PD patients with RLS;Inclusion criteria of RLS without PD
•1.Definite RLS in which all four revised minimal criteria of RLS are fulfilled based on an personal history taken by a RLS trained investigator/ doctor
•2.All secondary RLS patients are excluded besides iron deficiency related RLs
•3.Age and sex matched to the PD patients;Inclusion criteria healthy controls
•1. Definite no RLS or other known diseases
•2. Age and sex matched to the RLS patients without PD

•1.No temporal bone window to perform a qualitatively good transcranial sonography
•2.Iron medication
•3.Pregnancy

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