ISRCTN99195212已完成3 期
An open, randomised, multicentre trial of Tomudex (ZD1694) versus 5-Fluorouracil (5-FU) and Leucovorin (LV) in patients with advanced colorectal carcinoma
AstraZeneca Clinical Research Group (UK)0 个研究点目标入组 0 人开始时间: 2002年8月19日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Microscopically confirmed adenocarcinoma of the colon or rectum
- •2. Locally advanced, or metastatic (Dukes stage D) disease for which no curative therapy is available
- •3. Aged over 18 years
- •4. One or more measurable or evaluable lesions
- •5. World Health Organisation (WHO) performance status 0-2
- •6. Life expectancy of at least three months
- •7. Adequate bone marrow and liver function
排除标准
- •1. Previous systemic chemotherapy for colorectal cancer
- •2. Concomitant use of any systemic anticancer therapy
- •3. Adjuvant chemotherapy within the last 12 months
- •4. Concomitant administration of folic acid other than the trial therapy
- •5. Known brain metastases
- •6. Previous or concurrent malignancies at other sites, except adequately treated in-situ carcinoma of the cervix uteri and basal or squamous cell carcinoma of the skin
- •7. Other medical contraindications to treatment
研究者
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