JPRN-UMIN000031165
招募中
3 期
A phase III study of tri-modality combination therapy with induction docetaxel plus cisplatin and 5-fluorouracil (DCF) vs definitive chemoradiotherapy for locally advanced unresectable squamous cell carcinoma of the thoracic esophagus(JCOG1510,TRIANgLE) - A phase III study of tri-modality combination therapy with induction docetaxel plus cisplatin and 5-fluorouracil (DCF) vs definitive chemoradiotherapy for locally advanced unresectable squamous cell carcinoma of the thoracic esophagus(JCOG1510,TRIANgLE)
Japan Clinical Oncology Group (JCOG)0 个研究点目标入组 230 人2018年2月6日
概览
- 阶段
- 3 期
- 干预措施
- 未指定
- 疾病 / 适应症
- locally advanced unresectable squamous cell carcinoma of the thoracic esophagus
- 发起方
- Japan Clinical Oncology Group (JCOG)
- 入组人数
- 230
- 状态
- 招募中
- 最后更新
- 2年前
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- 未提供
排除标准
- •1\) Synchronous or metachronous (within 5 years) malignancy except cancer with 5\-year relative survival rate of 95% or more such as carcinoma in situ, intramucosal tumor, or early stage cancers. 2\) Prior surgery for head and neck superficial carcinoma within 5 years. 3\) Diagnosed with active infectious disease requiring systemic treatment by imaging or bacteriological inspections, and body temperature \>\= 38 degrees Celsius. 4\) Positive for HBs antigen or HIV antigen. 5\) Pregnancy, possible pregnancy, within 28 days after delivery or breast\-feeding. Male subjects who want pregnancy of their partner. 6\) Psychological disorder difficult to participate in this clinical study. 7\) Receiving continuous systemic corticosteroid or immunosuppressant treatment. 8\) Under treatment by flucytosine, phenytoin, or warfarin potassium . 9\) Previous histry of allergy to iodine. 10\) Diabetes mellitus uncontrollable with continuous use of insuline or hypoglycemic agents. 11\) Severe emphysema or pulmonary fibrosis based on chest CT. 12\) Uncontrolled arterial hypertension. 13\) History of unstable angina pectoris within three weeks or myocardial infarction within six months before registration. 14\) Uncontrolled valvular disease, dilated cardiomyopathy, and hypertrophic cardiomyopathy.
结局指标
主要结局
未指定
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