跳至主要内容
临床试验/NCT07029074
NCT07029074已完成不适用

Investigation of the Acute Effect of Inspiratory Muscle Training Applied at Different Intensities on Intercostal Muscle Oxygenation

Kirsehir Ahi Evran Universitesi2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年7月24日最近更新:
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
30
试验地点
2
主要终点
Evaluation of intercostal muscle oxygenation

研究概览

简要总结

In this study, it was aimed to investigate the acute effect of inspiratory muscle training of different intensities on intercostal muscle oxygenation in healthy individuals.

详细描述

The functional activity of the respiratory system must be regular and efficient in order to meet the oxygen needs of tissues and organs. The mechanical function of the respiratory system is significantly related to the working capacity of the respiratory muscles. The diaphragm is the primary muscle that provides respiratory functions among the respiratory muscles.The external intercostal muscles help with the inspiration, while the internal intercostal muscles help with the expiration. The basis of inspiratory muscle training is to reduce dyspnea, increase inspiratory muscle function and exercise tolerance. Inspiratory muscle training provides an increase in muscle strength by increasing inspiratory muscle strength, reducing metaboreflex activity and increasing blood flow to the muscles. Training is thought to minimize the effects of activation of inspiratory muscle metaboreflex in both healthy individuals and patients with heart failure. In chronic respiratory patients, forced inspiration effort reduces capillary perfusion of the respiratory muscles, thus increasing the oxygen demand of the muscle. Muscle oxygen saturation shows the oxygen uptake and oxygen consumption of the muscle. It aims to investigate the mechanisms involved in the metaboreflex response to respiratory fatigue in inspiratory muscle training, which severity will acutely reduce it more.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Physically active (doing moderate intensity physical activity for at least 3 days a week for 150 minutes / week)
  • Volunteer to participate in the study

排除标准

  • Healthy individuals with any diagnosed chronic or systemic disease,
  • Smoke 10 packs x years or more,
  • Pneumonia or any acute infection,
  • Psychiatric disorder will excluded in the study.

研究组 & 干预措施

Sham inspiratory muscle training (Maximal inspiratory pressure (MIP) 0%)

Experimental

Individuals participating in the study will be randomly assigned sham inspiratory muscle training sessions maximal inspiratory pressure of 0% under the supervision of a specialist physiotherapist for 15 minutes.

干预措施: Sham inspiratory muscle training (MIP 0%) (Device)

MIP 30% inspiratory muscle training

Experimental

Individuals participating in the study will be randomly assigned inspiratory muscle training sessions maximal inspiratory pressure of 30% under the supervision of a specialist physiotherapist for 15 minutes.

干预措施: MIP 30% inspiratory muscle training (Device)

MIP 70% inspiratory muscle training

Experimental

Individuals participating in the study will be randomly assigned inspiratory muscle training sessions maximal inspiratory pressure of 70% under the supervision of a specialist physiotherapist for 15 minutes.

干预措施: MIP 70% inspiratory muscle training (Other)

结局指标

主要结局

Evaluation of intercostal muscle oxygenation

时间窗: Second, Third and Fourth day

Before the inspiratory muscle training sessions, the muscle oxygen saturation (SmO2) of the intercostal muscles in recovery during and after the training session will be measured using a Moxy® monitor (Moxy, Fortiori Design LLC, Minnesota, USA).

Evaluation of intercostal muscle total hemoglobin level

时间窗: Second, Third and Fourth day

Before the inspiratory muscle training sessions, total hemoglobin level (THb) of the intercostal muscles in recovery during and after the training session will be measured using a Moxy® monitor (Moxy, Fortiori Design LLC, Minnesota, USA).

次要结局

  • Evaluation of respiratory muscle strength(First day)
  • Evaluation of respiratory muscle endurance(First day)
  • Evaluation of pulmonary function (Forced expiratory volume in the first second (FEV1))(First day)
  • Evaluation pulmonary function (Forced vital capacity (FVC))(First day)
  • Evaluation of pulmonary function (FEV1/FVC)(First day)
  • Evaluation of pulmonary function (Flow rate 25-75% of forced expiratory volume (FEF 25-75%))(First day)
  • Pulmonary function (Peak expiratory flow (PEF))(First day)
  • Evaluation of physical activity level(First day)

研究者

发起方
Kirsehir Ahi Evran Universitesi
申办方类型
Other
责任方
Principal Investigator
主要研究者

Başak KAVALCI KOL

Principle Investigator

Kirsehir Ahi Evran Universitesi

研究点 (2)

Loading locations...

相似试验