ACTRN12619001032145尚未招募3 期
Effect of nebulised furosemide on breathlessness and cough in interstitial lung disease: a pilot study
Hunter New England Health0 个研究点目标入组 12 人开始时间: 2019年7月18日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 12
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Age > 18 years
- •Confirmed physician diagnosis of an interstitial lung disease
- •Medical research council dyspnoea scale of 3-5
- •Cough visual analogue scale >4cm
- •FVC >=30% predicted
- •DLCO >=20% predicted
排除标准
- •Current smoker
- •Clinical history of asthma or vocal cord dysfunction
- •Currently pregnant or breastfeeding
- •Any clinically significant cardiopulmonary abnormalities not related to ILD, including features of congestive cardiac failure on examination or history suggestive of uncontrolled ischaemic heart disease.
- •Any clinically significant neurological, renal, endocrine, gastrointestinal, hepatic or haematological abnormalities uncontrolled with standard treatment
- •History of psychiatric, medical or surgical disorders that may interfere with study
- •Clinical history suggestive of respiratory infection in month preceding study
- •Alcohol or recreational drug abuse
- •Inability to understand directions for study assessment, including inability to comprehend English language.
- •Inability to complete questionnaires required for the study, including visual analogue scales.
- •Inability to be contacted in case of emergency
- •Participation in another study at the same time or within a prior 3-month period
- •Regular use of short or long-acting opioids, pregabalin or gabapentin.
- •Inability to complete a 6 minute walk test
- •Allergy or significant adverse reaction to furosemide
研究者
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