Effect of Rib Mobilization on Weaning Parameters From Mechanical Ventilator in Patients With Pneumonia
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Arterial blood gases
研究概览
简要总结
this study will be conducted to distinguish between effect of rib mobilization and routine chest physiotherapy on weaning parameters from mechanical ventilator in patients with pneumonia •
HYPOTHESES:
It will be hypothesized that there may be significant effect of rib mobilization on weaning parameters from mechanical ventilator in patients with pneumonia.
RESEARCH QUESTION:
Does rib mobilization have an effect on weaning parameters from mechanical ventilator in patients with pneumonia? measuring weaning parameters: on screen of mechanical ventilator : measuring respiratory rate, Tidal volume (TV), FiO2.
- Arterial blood gases (ABG) analyzer machine ABG is recorded daily (PH- PaO2 - PaCO2)
- Length of ICU stay: calculated by (admission date - discharge date
- Weaning success rate
详细描述
Ventilator-associated pneumonia (VAP) represents a significant sub-set of (HAP) remains the most frequent intensive care unit (ICU)-acquired infection its incidence ranges from 9% to 27% of ventilated patients ,VAP is associated with an increased length of stay, mortality and health care costs, Pneumonia can result in chest wall stiffness, decreased mobility, limiting the range of motion during breathing and decreased lung compliance and impaired respiratory function , Rib mobilization: is an articular , non-invasive, passive technique that can be useful with acutely ill, hospitalized patients emphasizes the placement of a repetitive force to increase the range of motion of the posterior rib articulations and chest wall , lessening somatic dysfunction of the spine, stretches myofascial structures and improve respiratory mechanics So, this study will be conducted to distinguish between effect of rib mobilization and routine chest physiotherapy on weaning parameters among intubated pneumonic patients on mechanical vent.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient's age ranged from 40- 50 years old from both genders.
- •Diagnosed with pneumonia and need invasive mechanical ventilation support.
- •Stable oxygen saturation (SpO2 more than 85, (FiO2) 0.6 or less, PEEP less than 10 Cm H2O).
- •mean arterial pressure > 75 mmHg and urine output > 1 mL/kg/h;
- •Patients with Glasgow coma scale (GCS) > 8T
- •Unconscious and semi-conscious patients. -
排除标准
- •Unstable hemodynamics
- •Unstable neurological problems e.g. (epileptic seizures -hyperthermia).
- •Unstable chest wall e.g. (multiple rib or vertebral fractures)
- •Increase intracranial pressure (>20 mmHg for >5 min).
- •Undrained pneumothorax, recent pulmonary surgery
研究组 & 干预措施
rib mobilization technique and routine chest physiotherapy group
1.rib mobilization technique and routine chest physio therapy group: the patients will receive rib mobilization technique in addition to their medical treatment and routine chest physiotherapy for at least 30 minutes once daily for ten consecutive days
干预措施: rib mobilization technique (Other)
rib mobilization technique and routine chest physiotherapy group
1.rib mobilization technique and routine chest physio therapy group: the patients will receive rib mobilization technique in addition to their medical treatment and routine chest physiotherapy for at least 30 minutes once daily for ten consecutive days
干预措施: routine chest physiotherapy (Other)
routine chest physiotherapy group
routine chest physiotherapy group : the patients in this group will receive routine chest physical therapy for at least 30 minutes once daily for 10 consecutive days
干预措施: routine chest physiotherapy (Other)
结局指标
主要结局
Arterial blood gases
时间窗: at least 10 consecutive days
• Arterial blood gases (ABG): (PH -PaO2 - PaCO2) • PaO2/FiO2 ratio (P/F): One element of predicting successful weaning from mechanical ventilation is PaO2/FiO2 \> 200
Respiratory rate (RR)
时间窗: at least 10 consecutive days
It will be measured using a mechanical ventilator.
Tidal volume (TV)
时间窗: at least 10 consecutive days
It will be measured using a mechanical ventilator.
次要结局
- Length of hospital stay(at least 10 consecutive days)
研究者
Hoda Gaber
Principal Investigator
Cairo University