Pain Relieving Effect of Glycerol Trinitrate (GTN) in Renal Colic

Not Applicable

Recruiting

• Conditions: Renal Colic.; Unspecified renal colic

• Registration Number: IRCT20180428039443N2
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 April 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Patients over 16 years of age, who are clinically diagnosed by an emergency physician with imaging (ultrasound or CT scan) to have renal colic and have a pain level higher than 5 on the VAS scale).
Patients who have treated themselves or had side effects from diseases such as gastrointestinal, heart, kidney or liver are not included.
The following will be considered as exclusion criteria: symptoms of peritoneal irritation, pregnancy and lactation, fever or hypotension; History of sildenafil, tadalafil, vardenafil, antihypertensive drugs, aspirin, antimuscarinic, alcohol, ergotamine, haloperidol or phenothiazine during the last 4 weeks,

Exclusion Criteria

allergic reaction to GTN;
Severe clinical anemia; Recent concussion or any damage to the central nervous system, malnutrition, hypothyroidism; Hypothermia; And drug abusers.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain Relieving. Timepoint: Pain will be measured again in patients after 5 minutes, and if the VAS pain is still more than 5, the patient will receive another 30 mg of ketorolac injection. Pain will be re-estimated 30 minutes after this dose, and if the patient has a VAS pain score higher than 5, the next dose of ketorolac will be injected. Method of measurement: Response to VAS treatment is defined as less than 5.