IRCT20220102053599N1已完成3 期
Comparison of the effect of ketorolac and intravenous lidocaine on fentanyl-induced cough in patients undergoing elective surgery: a Double-blind clinical trial
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 210
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 60 years（—）
- 性别
- All
入选标准
- •aged 18 to 60 years, with and with, who
- •referred to Firoozgar and Hazrat Rasul-e Akram hospitals and are candidates for elective surgery that lasts more than an hour
- •in the period of April 2022 to June 2022
排除标准
- •Preoperative pulmonary emphysema
- •Bronchial asthma
- •History of upper respiratory infection during the last 2 weeks
- •Hypertension
- •Coronary artery disease
- •Has a chronic cough that makes it difficult to diagnose fentanyl-induced cough
- •High pressure inside the eyes, brain or abdomen
- •Taking anti-anxiety and anti-depressant drugs before surgery
- •Taking anti-cough medicines (codeine, dextromethorphan, baclofen, steroids or bronchodilators) during the last week
- •BMI above 28 kg/m2
- •History of chronic opioid use
- •Taking cough medicines (ACEI & ABR)
- •History of GERD or peptic ulcer
- •History of kidney or liver disease
- •Pregnancy or breastfeeding
- •Known allergy to fentanyl or ketorolac
- •G6PD deficiency disease
- •High risk of GIB
- •Patient reluctance
研究者
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