Best Assessment of Sore Throat and Antibiotic Prescribing
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 450
- 试验地点
- 4
- 主要终点
- Guideline adherence
研究概览
简要总结
This project aims to investigate if an organisational change of patient flow away from medical practitioners can reduce unnecessary antibiotic prescribing in patients attending with a sore throat as the main complaint.
详细描述
Today patients appear either at a PHC centre or at the Pharmacy. The Pharmacy may provide advice on analgesic or refer the patient to a PHC centre. At the PHC centre, the patient may first appear to the medical practitioner or a nurse pending on local routines. The current Swedish guideline recommends no antibiotics and no testing for patients with 0-2 Centor criteria. For patients with 3-4 Centor criteria the guideline recommends testing and only consider antibiotics if GAS is present.
COVID-19 has gradually transformed from expressing itself as a severe lower respiratory tract infection to be more of an upper respiratory tract infection. Furthermore, COVID-19 is likely to transform from a pandemic to an endemic state with a low continuous incidence. Hence, in response to COVID-19 it seems crucial to identify to what extent the common sore throat is caused by the SARS-CoV-2.
Furthermore, a large controlled clinical trial is required to sort out if patients attending with a sore throat as the main complaint are best managed by medical practitioners, nurses or pharmacists. This study aims to perform such a controlled clinical trial comparing the outcome of sore throat patients management by medical practitioner, nurses and pharmacists. This study also aims to investigate to what extent the SARS-CoV-2 virus is identified in these patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 6 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The patient is contacting/attending PHC centre or Pharmacy presenting with a sore throat as the main complaint.
- •Male or female, aged ≥6 years.
- •Fluent in Swedish (reading, writing, conversational) (applicable to caregivers/parents/guardians in case of children).
- •Mental state such that he or she can understand and give informed consent to participation in the study by signing the Information and Consent Form.
- •Provision of signed and dated Informed Consent Form.
排除标准
- •The illness episode is classified as potentially complicated or potentially critically ill
- •Presence of SARS-CoV-2 virus in a patient first appearing at the PHC in a cluster where the assessment is supposed to be done by the pharmacists. The patient will not be sent to the pharmacist in case of presence of SARS-CoV-2-virus.
- •Patient request to be withdrawn from the study.
研究组 & 干预措施
Initial assessement by physicians
Patients attending with an acute sore throat are initially assessed by a physician. This is one variant of current standard practice.
干预措施: Physicians assess patients (Behavioral)
Initial assessement by nurses
Patients attending with an acute sore throat are initially assessed by a nurse. This is one variant of current standard practice.
干预措施: Nurses assess patients (Behavioral)
Initial assessement by pharmacists
Patients attending with an acute sore throat are initially assessed by a pharmacist. This is officially not standard practice in Sweden, although it happens.
干预措施: Pharmacists assess patients (Behavioral)
结局指标
主要结局
Guideline adherence
时间窗: Immediately after the consultation
Will the proportion of patients attending for an uncomplicated acute sore throat being managed according to prevailing guidelines differ if the initial assessment is made by a medical practitioner, a trained nurse or a trained pharmacist
次要结局
- Type of patients seeking care(Immediately after the consultation)
- Presence of SARS-CoV-2 virus(Immediately after the consultation)
- Illness severity(Immediately after the consultation)