NCT02823132已完成不适用
Study of the Level of Mannose Binding Lectin (MBL) as a Predictor of the Onset of a Invasive Fungal Infection (IFI) During Chemo-induced Aplasia in Patients With Acute Leukemia (AL)
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 134
- 试验地点
- 1
- 主要终点
- serum level of Mannose Binding Lectin (MBL) in patients with acute leukemia
研究概览
简要总结
The aim of this study is to investigate levels of a protein, mannose binding lectin, in patients with acute leukemia who develop or not an invasive fungal infection.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •Patients who have received an bone marrow PSC allograft (as such patients have a risk of aspergillosis, which appears in most cases after medullar recovery; they will not be included in the study).
- •Patients who have received an autologous PSC graf (as the duration of neutropenia is in most cases less than 10 days).
- •Patients whose neutropenia, retrospectively assessed, lasted less than 10 days.
结局指标
主要结局
serum level of Mannose Binding Lectin (MBL) in patients with acute leukemia
时间窗: 1st day of the period of aplasia
次要结局
- Serum levels of MBL during an episode of aplasia for both groups of patients studied(Every day except Saturday and Sunday for roughly 3 weeks)
研究者
研究点 (1)
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