To measure how much of egg protein is taken up by the body for its use
Not Applicable
- Registration Number
- CTRI/2018/03/012265
- Lead Sponsor
- DBT Wellcome Trust Margadarshi Fund
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
BMI between18.5 to 25 Kg/m²
Exclusion Criteria
History of smoking or taking other leisure drugs
Consumption of alcohol in the previous 24 hours
History of antibiotic usage 4 weeks prior to the study
On iron supplementation therapy (3 months)
On medication such as NSAIDâ??s, proton pump inhibitors or H2 blockers 2 days prior to and on the study day
Participation in any nutritional study in the last 6 months
History of food allergy, specifically to egg or meat protein
Diagnosed with chronic medical or surgical illness
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Protein Digestibility measures of intrinsically 2H labeled egg and poultry meat protein in healthy adult humans using the dual tracer approachTimepoint: Blood sampling time points for digestibility measurement include half hourly once from 5th hour to 8th hour
- Secondary Outcome Measures
Name Time Method Comparison between the mean digestibilities of the two methods of egg protein processed test meal fed to the subjectsTimepoint: Average of 7 blood time point enrichment values will be taken for digestibility calculation and compared between two methods of processing;Determination of the functional status of the intestine using plasma kynurenine and KT ratio to rule of any effect of poor intestinal health on the digestibilityTimepoint: Basal (1 time point) plasma sample will be used for analysis and determination of plasma kynurenine and KT ratio;Determine the influence of tea polyphenol on whole egg individual true ileal digestibilityTimepoint: Average of 7 time points plasma enrichment values will be used for digestibility calculation and a comparison between true ileal IAA digestibility of egg with and without tea polyphenol will be made