Short- and Long-term Health Effects of Air Pollution in Poland
- Conditions
- Acute Coronary SyndromeAtrial FibrillationParticulate Matter Inhalation InjuryPollution; ExposureKidney DiseasesIschemic StrokeOxidative Stress
- Registration Number
- NCT05198492
- Lead Sponsor
- Medical University of Bialystok
- Brief Summary
The effects of air pollution on the frequency of hospital admissions and mortality due to acute coronary syndromes, atrial fibrillation, and renal disfunction are noted also in areas perceived as pollution-free (due to the lack of large industry). The aim of the project is to assess the impact of air pollution in Eastern Poland on regional public health.
- Detailed Description
The project will be conducted in Eastern Poland - the area characterized by unique natural features, large areas covered by forests, lack of factories, and relatively low industrialization. On the other hand, the region is also characterized by low socioeconomic status, in the cold season the residents' suboptimal heating choices are in result posing a major anthropogenic threat to air quality in the form of low emissions. The vast majority of studies on air pollution were conducted in highly polluted areas, in which patients are exposed to moderate and extreme concentrations of pollutants. Taking into consideration the scarce number of surveys from areas with a low level of pollution the investigators intend to analyze the relationship between air pollution and cardiovascular and renal outcomes in Eastern Poland. The examination of the impact of so-called "Polish smog" on mortality and morbidity in the study area is not without significance. It would be the first major study of the impact of this type of pollution on human health.
In the subsequent part of the study, we will evaluate the effects of Polish smog in the entire country.
In light of extant body of literature, the following will be considered as the public health indicators: acute coronary syndromes, episodes of atrial fibrillation, ischemic strokes, kidney disease hospitalizations or emergency room visits, cardiovascular and renal mortality.
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 8300000
- Residents from the analyzed area
- None
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Number of hospitalizations due to kidney diseases related to the impact of air pollution. Through study completion, an average of 1 year Long- term influence of air pollution on the number of hospital admissions for kidney disease.
Number of atrial fibrillation episodes related to the impact of air pollution. Through study completion, an average of 1 year Short- and long- term influence of air pollution on the number of hospital admissions for atrial fibrillation.
Number of hospitalizations due to acute kidney diseases related to the impact of air pollution. Through study completion, an average of 1 year Long- term influence of air pollution on the number of hospital admissions for kidney disease.
Number of patients under hemodialysis related to the impact of air pollution. Through study completion, an average of 1 year Long- term influence of air pollution on the number of hospital admissions for kidney disease.
Number of acute coronary syndromes related to the impact of air pollution. Through study completion, an average of 1 year Short- and long- term influence of air pollution on the number of hospital admissions for acute coronary syndromes.
Number of ischemic strokes related to the impact of air pollution. Through study completion, an average of 1 year Short- and long- term influence of air pollution on the number of hospital admissions for ischemic strokes.
- Secondary Outcome Measures
Name Time Method Neoplasm mortality Through study completion, an average of 1 year Short- and long- term influence of air pollution on neoplasm mortality.
Cardiovascular mortality Through study completion, an average of 1 year Short- and long- term influence of air pollution on the number of cardiovascular mortality.
Kidney disease mortality Through study completion, an average of 1 year Short- and long- term influence of air pollution on mortality related to renal function.
Related Research Topics
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Trial Locations
- Locations (1)
Department of Invasive Cardiology, Medical University of Bialystok
🇵🇱Białystok, Podlaskie, Poland
Department of Invasive Cardiology, Medical University of Bialystok🇵🇱Białystok, Podlaskie, Poland