Short- and Long-term Health Effects of Air Pollution in Poland
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 8,300,000
- 试验地点
- 1
- 主要终点
- Number of hospitalizations due to kidney diseases related to the impact of air pollution.
研究概览
简要总结
The effects of air pollution on the frequency of hospital admissions and mortality due to acute coronary syndromes, atrial fibrillation, and renal disfunction are noted also in areas perceived as pollution-free (due to the lack of large industry). The aim of the project is to assess the impact of air pollution in Eastern Poland on regional public health.
详细描述
The project will be conducted in Eastern Poland - the area characterized by unique natural features, large areas covered by forests, lack of factories, and relatively low industrialization. On the other hand, the region is also characterized by low socioeconomic status, in the cold season the residents' suboptimal heating choices are in result posing a major anthropogenic threat to air quality in the form of low emissions. The vast majority of studies on air pollution were conducted in highly polluted areas, in which patients are exposed to moderate and extreme concentrations of pollutants. Taking into consideration the scarce number of surveys from areas with a low level of pollution the investigators intend to analyze the relationship between air pollution and cardiovascular and renal outcomes in Eastern Poland. The examination of the impact of so-called "Polish smog" on mortality and morbidity in the study area is not without significance. It would be the first major study of the impact of this type of pollution on human health.
In the subsequent part of the study, we will evaluate the effects of Polish smog in the entire country.
In light of extant body of literature, the following will be considered as the public health indicators: acute coronary syndromes, episodes of atrial fibrillation, ischemic strokes, kidney disease hospitalizations or emergency room visits, cardiovascular and renal mortality.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Residents from the analyzed area
排除标准
- 未提供
结局指标
主要结局
Number of hospitalizations due to kidney diseases related to the impact of air pollution.
时间窗: Through study completion, an average of 1 year
Long- term influence of air pollution on the number of hospital admissions for kidney disease.
Number of atrial fibrillation episodes related to the impact of air pollution.
时间窗: Through study completion, an average of 1 year
Short- and long- term influence of air pollution on the number of hospital admissions for atrial fibrillation.
Number of hospitalizations due to acute kidney diseases related to the impact of air pollution.
时间窗: Through study completion, an average of 1 year
Long- term influence of air pollution on the number of hospital admissions for kidney disease.
Number of patients under hemodialysis related to the impact of air pollution.
时间窗: Through study completion, an average of 1 year
Long- term influence of air pollution on the number of hospital admissions for kidney disease.
Number of acute coronary syndromes related to the impact of air pollution.
时间窗: Through study completion, an average of 1 year
Short- and long- term influence of air pollution on the number of hospital admissions for acute coronary syndromes.
Number of ischemic strokes related to the impact of air pollution.
时间窗: Through study completion, an average of 1 year
Short- and long- term influence of air pollution on the number of hospital admissions for ischemic strokes.
次要结局
- Neoplasm mortality(Through study completion, an average of 1 year)
- Cardiovascular mortality(Through study completion, an average of 1 year)
- Kidney disease mortality(Through study completion, an average of 1 year)
研究者
Lukasz Kuzma
Principal Investigator
Medical University of Bialystok