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Clinical Trials/NCT07292311
NCT07292311
Active, not recruiting
Not Applicable

Reliability of Muscle Strength and Activation Assessment Tools and Effects of an Online Therapeutic Exercise Program in Patients With Chronic Kidney Disease

University of Extremadura1 site in 1 country50 target enrollmentStarted: November 7, 2025Last updated:

Overview

Phase
Not Applicable
Status
Active, not recruiting
Sponsor
University of Extremadura
Enrollment
50
Locations
1
Primary Endpoint
Test-retest reliability of surface EMG (Electromiography) activation.

Overview

Brief Summary

This research aims to evaluate the reliability and reproducibility of muscle strength and activation measurement tools, including isokinetic dynamometry and surface electromyography, in patients with chronic kidney disease (CKD). Additionally, the study will assess the feasibility and potential benefits of an online therapeutic exercise program supervised by physiotherapists.

Detailed Description

Patients with chronic kidney disease experience progressive muscle weakness and reduced physical capacity due to systemic inflammation, metabolic acidosis, and inactivity.

This two-phase observational and interventional study, conducted in collaboration with the ALCER Association (Badajoz and Cáceres, Spain), will:

  1. Determine the test-retest reliability of muscle assessment tools (isokinetic dynamometer, surface electromyography, and handheld dynamometry).
  2. Implement and evaluate an online therapeutic exercise program supervised by physiotherapists.

The project aims to provide valid and reliable protocols for neuromuscular assessment in CKD patients and explore the feasibility of remote therapeutic exercise.

Study Design

Study Type
Interventional
Allocation
Non Randomized
Intervention Model
Single Group
Primary Purpose
Diagnostic
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • ≥18 years old.
  • Diagnosis of chronic kidney disease (hemodialysis, peritoneal dialysis, or kidney transplant).
  • Member of ALCER Association (Badajoz or Cáceres).
  • Medical clearance for physical testing/exercise.

Exclusion Criteria

  • Severe cognitive or communication impairment.
  • Unstable cardiovascular or musculoskeletal conditions.
  • Refusal to provide informed consent.

Outcomes

Primary Outcomes

Test-retest reliability of surface EMG (Electromiography) activation.

Time Frame: 7-10 days

RMS (root mean square). microvolts

Test-retest reliability of isokinetic strength

Time Frame: 7-10 days

Intraclass Correlation Coefficient - ICC. Strength (kilograms)

Change in handgrip and limb strength measured by VALD dynamometry

Time Frame: Baseline and 12 weeks

strength (kilograms)

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
University of Extremadura
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Alejandro Caña Pino

Investigator

University of Extremadura

Study Sites (1)

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