The link between physical fitness and the reward system in schizophrenia
- Conditions
- F20-F29Schizophrenia, schizotypal and delusional disorders
- Registration Number
- DRKS00023907
- Lead Sponsor
- Klinik für Psychiatrie, Psychosomatik und PsychotherapieUniversitätsklinikum Frankfurt
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
stable medication regime, regular and long antispychotic intake
pregnancy, use of amphetamines or cocaine within the last four weeks, no relevant clinical neurologycal illness
MRI contraindications: fever, pacemakers, infusion pumps, metal plates, screws (e.g. after a bone fracture), implants, protheses (e.g. shunts, stents aneurysm clips), injuries with metaldust or shrapnel, tattoos or permanent makeup, pregnancy, IUD (intrauterine device), claustrophobia, dentures, dental implants, bridges, braces or retainers (which are not removable)
In addition piercings and nicotine patches must be removed, the same applies to hearing aids, removable braces dentures and soft contact lenses. Bras with metal parts should be removed. The subject should not wear any make up.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method rewardsystem measured in the striatum, one time measurement, MRI (fMRI-BOLD-response)
- Secondary Outcome Measures
Name Time Method physical fitness test , anthropometric measures e.g. Chester-Step-Test