Efficacy and safety of tetracaine eye drops as a topical skin anesthesia in decreasing pain prior to botulinum toxin type A injections in blepharospasm patients
Phase 3
- Conditions
- The patients with confirmed diagnosis of blepharospasm, who undergo botulinum toxin A treatment in botulinum toxin clinic. Department of Ophthalmology, King Chulalongkorn Memorial HospitalBotulinum toxin, Blepharospasm, Pain, Tetracaine
- Registration Number
- TCTR20230530007
- Lead Sponsor
- Faculty of medicine, Chulalongkorn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 17
Inclusion Criteria
1. Patients of age more than 18 years
2.Diagnosed with Blepharospasm both eye by experienced neuro-ophthalmologists
3.Received the latest BoNT-A injection for more than 3 months
Exclusion Criteria
1.Allergic reaction to Botulinum toxin type A
2.Neuromuscular diseases
3.Any active infection in treatment area
4.Receiving anticoagulants
5.Diagnosed with bleeding disorders
6.Patients undergone prior facial cosmetic surgical procedure, such as eyebrow lift and others periorbital surgery
7.Patients with psychological disease
8.Patients with different severity of Blepharospasm
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain After finish intervention Visual analog scale
- Secondary Outcome Measures
Name Time Method Complication after application tetracaine eye drops as a topical skin anesthesia After finish intervention 30 min Assess complication after application tetracaine eye drops as a topical skin anesthesia