Postdischarge nutrition in infants born <32 weeks gestation and/or <1500 grams birth weight: relation with growth, body composition and metabolic health at 7 years (STEP 2)

Completed

Conditions: hypertension
metabolic syndrome
10021112

Registration Number: NL-OMON39311

Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 120

Inclusion Criteria

Participants of STEP 1 study. In short, infants born with gestational age 32 weeks or less and/or birth weight 1500 gram or less.

Exclusion Criteria

Gastro-intestinal surgery and disease known to influence growth; known presence of growth hormone, IGF-1 or other pituitary hormone deficiencies; cardiac, renal, pulmonary and liver disease; chromosomal and/or genetic syndromes; known presence of rickets, osteopenia or other skeletal disease; severe illness; concurrent therapies with substances known or suspected to be associated with alteration of growth.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are anthropometry (height, weight, head circumference<br /><br>and body proportions), body composition and salt sensitivity of blood pressure<br /><br>at 7 years of age.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secundary study parameters are endocrine factors (IGF-1, cortisol, leptine<br /><br>o.a.), cholesterol, psychomotore development, cognitieve development and bone<br /><br>mineralisation.</p><br>