Comparing improvement of lesions in leishmaniasis patients with two treatment methods including trichloroacetic Acid (TCA) and interalesional meglumine antimoniate (Glucantime) for the treatment of Lupoid leishmaniasis

Phase 2

• Conditions: Cutaneous Leishmaniasis.; Cutaneous Leishmaniasis

• Registration Number: IRCT201101313862N6
• Lead Sponsor: Research Council of Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

presence of cutaneous leishmaniasis in less than 6 months prior to the study that their disease has been approved by direct smear and stained with Giemsa or positive dermal biopsy, 3-month treatment-free interval from the last treatment course
Exclusion criteria: pregnancy, breast-feeding, any administration of any other medication during the study that has anti-leishmaniasis ingredient during 2 last months, history of severe renal impairment, pulmonary and cardiovascular disease

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Complete healing. Timepoint: first time at 8th weeks after treatment and the second time in follow up visit after 3 months of commencement of the study. Method of measurement: Measuring the width and induration and ulcer size.

Secondary Outcome Measures

Name	Time	Method
Side effects. Timepoint: at each follow up visit. Method of measurement: Physical examination.