A Prospective, Non-Randomized, Multi-Center Observational Study to Establish a Physical Baseline Profile for Individual Study Subjects Using Various Modalities and Identify Deviations Via Longitudinal Monitoring That May Develop Over Time
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Aging
- Sponsor
- Puer Research, LLC
- Enrollment
- 10000
- Locations
- 1
- Primary Endpoint
- Biomarkers that exhibit significant change
- Status
- Enrolling By Invitation
- Last Updated
- last year
Overview
Brief Summary
This is a minimal risk, prospective, non-randomized, multi-center population based observational study to establish a physical baseline profile for individual study subjects using various modalities (blood draws, non-invasive imaging, stool samples, saliva samples) and identify deviations through longitudinal monitoring that may develop over time and may be relevant to human health and healthy longevity.
Detailed Description
The two key elements of the PUER Research protocol include (1) molecular and laboratory profiling and (2) non-invasive imaging and wearables/ "quantified self" measurements. All elements are optional. Molecular assessments will be conducted using peripheral blood samples, and potentially urine, stool or saliva samples. Non-invasive imaging assessment will consist of magnetic resonance imaging (MRI) and computerized tomography (CT) scans, ultrasound, and x-ray. All imaging modalities are optional. Other functional assessments, including respiratory, cardiac and other functions, as well as self-quantifiable assessments via wearables, may also be conducted and are optional. The study will result in longitudinal data collection to inform if any modalities employed here can inform of baseline deviations for individuals. Researchers at study sites will not be blinded to the data being collected during this study.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Male or non-pregnant female; age 18 to 90
- •Absence or presence of any medical history or any signs or symptoms of any disease
- •Women of childbearing potential (WOCBP) must have a negative urine pregnancy test (UPT) at all visits
Exclusion Criteria
- •Unwillingness or inability to participate in the study
- •Unwillingness or inability to provide written Informed Consent Form
- •WOCBP with positive pregnancy test at enrollment or at any visit
Outcomes
Primary Outcomes
Biomarkers that exhibit significant change
Time Frame: 12 Months
The number of biomarkers that exhibit significant change from baseline to any follow-up timepoint, if obtained.