Randomized study to compare individualized positive end-expiratory pressure and fixed positive end-expiratory pressure in patients receiving mechanical ventilation in the prone positio
Not Applicable
- Conditions
- Not Applicable
- Registration Number
- KCT0009405
- Lead Sponsor
- Ajou University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
A. Adult patients aged 19 years or older undergoing surgery in the prone position with an estimated operating time of 60 minutes or more.
B. American Society of Anesthesiologists physical status classification (ASA physical status classification) grade 1-2
Exclusion Criteria
A. Patients who did not consent to the study
B. American Society of Anesthesiologists physical status classification (ASA physical status classification) grade 3-4
C. Patients requiring mechanical ventilation after surgery
D. Patients with contraindications to positive end-expiratory pressure (pneumothorax, large bullae, hypovolemic shock, etc.)
E. Patients deemed unsuitable for this clinical study according to the opinion of the researcher or research staff
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ung ultrasound score
- Secondary Outcome Measures
Name Time Method ung ultrasound score;respiratory variable (PaO2, PaO2:FiO2 ratio, driving pressure, static lung compliance, peak inspiratory pressure, plateau pressure);Total amount of fluid and transfusion;Types and dosages of vasoactive drugs;Incidence of hypoxemia (SpO2<92%);Incidence of pulmonary complications (hypoxemia (SpO2<92%), oxygen therapy within 2 days after surgery, mechanical ventilation for more than 24 hours, re-intubation, atelectasis confirmed by imaging, pneumonia, ARDS, postoperative acute lung injury, pleural effusion);Incidence of pulmonary complications (Dyspnea, pneumonia, respiratory-related readmission, etc.)