KCT0006834
Recruiting
未知
Hospital-based cohort study of aged people with dementia
ConditionsDiseases of the nervous system
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Diseases of the nervous system
- Sponsor
- Samsung Medical Center
- Enrollment
- 550
- Status
- Recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\) Adult men and women over the age of 60
- •2\) After listening to and fully understanding the detailed explanation of this study, the subject or legal representative voluntarily decides to participate in the study and gives written consent
- •Subjective Cognitive Dysfunction (SCD)
- •1\) MMSE score above mean\-1 SD when considering age, gender, and education level
- •2\) Subjects who are willing and able to cooperate with this study and complete all clinical trial stages
- •Mild cognitive impairment (aMCI)
- •1\) Patient or guardian complains of cognitive impairment
- •2\) Through an objective neuropsychological test, it was confirmed that cognitive ability including memory is lower than age and education.
- •3\) Maintain overall cognitive function
- •4\) No disruption to daily life
Exclusion Criteria
- •Exclusion from this study is required if one or more of the following conditions are met
- •1\) Patients with neurological abnormalities that may cause memory impairment on medical examination
- •2\) Those with a history of uniaxial psychiatric disorders including intellectual disability, schizophrenia, alcoholism, and bipolar disorder in the past
- •3\) Those with a history of malignant disease (cancer) within the last 3 years. Except for cervical carcinoma in situ or non\-melanoma skin cancer.
- •4\) Those who have undergone cerebrovascular surgery, such as brain surgery or carotid artery surgery
- •5\) Those who have neurological symptoms that are evidence of cerebrovascular disease, such as extrapyramidal signs consistent with subcortical lesions
- •6\) Those who have difficulty breathing when sitting still
- •7\) Thyroid stimulating hormone (TSH), folic acid, vitamin B12, apoE gene (APOE), RPR test (syphilis test) during blood test
- •A person whose result is an abnormal value and the abnormal value continues even after the relevant treatment
- •8\) Those who have had memory impairment, language impairment, or problem\-solving ability for more than 2 hours after a heart attack
Outcomes
Primary Outcomes
Not specified
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