Clinical and Digital Radiographic Evaluation of Simvastatin Versus MTA in Pulpotomy of Immature Permanent Vital Molars: A18 Month Randomized Controlled Trial
试验速览
- 阶段
- 早期 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 128
- 试验地点
- 1
- 主要终点
- Presence or absence of pain
研究概览
简要总结
the study will be done to evaluate the clinical and digital radiographic success of simvastatin versus MTA in pulpotomy of immature permanent molars
详细描述
the clinical and digital radiographic success of simvastatin versus MTA in pulpotomy of immature permanent molars for the following patients which include: Healthy children aged from 6 to 8 years who will be classified as Class I or II Children according to the American Society of Anaesthesiologists (ASA) will be included. Children with severe behavioral, or emotional disabilities, and medically compromised children will be excluded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 6 Years 至 8 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Healthy children aged from 6 to 8 years
- •Children with severe behavioral, or emotional disabilities, and medically compromised children will be excluded.
- •Deep carious lesions of the first permanent immature molars with signs & symptoms of reversible pulpitis will be included
- •Normal radiographic findings and immature roots
排除标准
- 未提供
研究组 & 干预措施
simvastatin
Drug The drug powder will be mixed with distilled water to form a paste applied in the pup chamber of immature permanent molars over the pulp stump
干预措施: Simvastatin (Drug)
Mineral Trioxide Aggregate
Dental material It is a regenrative endodontic material prepared as apoweder that mixed with distilled water to form a paste applied in the pup chamber of immature permanent molars over the pulp stump
干预措施: Simvastatin (Drug)
结局指标
主要结局
Presence or absence of pain
时间窗: one year
clinical assessment
次要结局
- Dentin wall thickness(18 months)
研究者
Ahmad Elheeny
clinical professor
Minia University