JPRN-UMIN000000560已完成2 期
Phase II trial of dosetaxel and carboplatin as neoadjuvant chemotherapy in patients with stage Ib2-II nonsquamous cell carcinoma of uterine cervix - Phase II trial of dosetaxel and carboplatin as neoadjuvant chemotherapy in patients with stage Ib2-II nonsquamous cell carcinoma of uterine cervix
Sankai Gynecology Study Group (SGSG)0 个研究点目标入组 61 人开始时间: 2007年1月1日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 61
研究概览
简要总结
The response rate was 69 % (95 % CI, 57-82 %), with 5 patients achieving complete response, 31 partial response, 15 stable disease, and 1 progressive disease. Median follow-up duration was 1913 days with a range of 145-2632 days. Of 52 patients, 50 underwent radical hysterectomy after neoadjuvant chemotherapy. The 2-year overall survival rate was 81.8 % for stage IB2, 85.7 % for stage IIA2, and 92.6 % for stage IIB.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 75years-old（—）
- 性别
- Female
入选标准
- 未提供
排除标准
- •1 fever with over 38.0C 2 infection or WBC>12,000/mm3 3 severe complications 4 neuropathy >Grade 2 5 edema > Grade 2 6 double cancer 7 pleural effusion and ascites for which drainage are necessary. 8 previous chemotherapy by taxane compounds
研究者
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