Walking Alteration for Knee osteoarthritis, the WALK study. An RCT*

Withdrawn

Conditions: arthrosis
knee osteoarthritis
10023213

Registration Number: NL-OMON46305

Lead Sponsor: Maxima Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Withdrawn

Sex: Not specified

Target Recruitment: 144

Inclusion Criteria

- Symptomatic knee OA according to the clinical ACR criteria
- Radiographic OA, according to Kellgren and Lawrence grade 1, 2 or 3
- Flexion contracture of 5 degrees or more, measured with a goniometer

Exclusion Criteria

- Medial or lateral instability of the knee,
o Medial or lateral joint space opening of * 5 mm in 20° of knee flexion is considered as unstable.
- Symptomatic bilateral knee OA
- Intra-articular injection of the knee, in the previous 3 months
- Previous peri-articular osteotomy of the affected knee
- Symptomatic OA of hip or ankle
- Co morbidity which disables the function of the lower extremity
- Rheumatoid Arthritis or other inflammatory joint disease
- Physical therapy for current complaints during last 3 months
- Insufficient command of the Dutch language
- Legally incompetent adults

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Between group difference in change in pain / function score between baseline<br /><br>and 3 months follow-up. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcomes are OMERACTOARSI set of responder criteria, KOOS, NRS pain,<br /><br>EQ-5D, ICOAP, need for TKA* OARSI-criteria, gait parameters as assessed by<br /><br>gait analyses (duration of full extension and quadriceps muscle activity during<br /><br>midstance of walking cycle) , and medication use. To get more insight in which<br /><br>specific patients will respond on the current intervention also the HADS,<br /><br>Central Sensitization Inventory, pain drawing form and pain cognition list will<br /><br>be evaluated. </p><br>