Effects of Pelvic Tilt Exercises Along With Hip and Knee Focused Exercises on Patients With Patellofemoral Pain Syndrome

Not Applicable

Active, not recruiting

• Conditions: Patellofemoral Pain Syndrome

• Registration Number: NCT06913426
• Lead Sponsor: Superior University

Brief Summary

This study is designed as a Randomized Controlled Trial to be conducted at the CRC Department of Chaudhary Muhammad Akram Teaching and research Hospital, Lahore.

Detailed Description

A total of 48 participants will be recruited accounting for a 10% dropout rate (42+6=48) and equally divided into two groups 24 participants in each group: Group A(Intervention) and Group B(Control). Participants will be selected based on inclusion criteria which includes individuals aged 35-55 years with a clinical diagnosis of Patellofemoral Pain Syndrome (positive Patellar Compression Test) symptoms persisting for at least 6 weeks to 6 months and moderate-to-severe knee pain (NPRS ≥ 4). They must also be willing to comply with study protocols. Exclusion criteria include recent knee surgery, other knee conditions (e.g., ligament injuries or severe osteoarthritis), and neurological disorders affecting movement or cognition.

Study Timeline

• Status Verified: 2025-03
• Study Start: 2025-03-20
• Study First Submitted: 2025-03-29
• Study First Submitted QC: 2025-03-29
• Last Update Submitted: 2025-03-29
• Study First Posted: 2025-04-06
• Last Update Posted: 2025-04-06
• Primary Completion: 2025-06-20
• Study Completion: 2026-02-20

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

• Participants must have a clinical diagnosis of Patellofemoral Pain Syndrome.
• Participants should be aged between 35 and 55 years, as this is the typical age group affected by PFPS and will help standardize the sample.
• Individuals with a BMI ranging from 18 to 25 kg/m2.
• Participants should have had symptoms of PFPS for at least 6 weeks to 6 months, ensuring the condition is subacute and chronic.
• Knee Pain Severity: Patients must report moderate to severe knee pain (e.g., pain score ≥ 4 on a 0-10 pain scale) to assess the effectiveness of rehabilitation interventions.
• Participants must be willing to engage in the prescribed exercise program and comply with study protocols including follow-up assessments.

Exclusion Criteria

• Individuals who have undergone knee surgery within the last 6 months, as post-surgical rehabilitation could interfere with the study outcomes and confound results. Patients with other knee conditions, such as ligament injuries (e.g., ACL or MCL tears), meniscal tears or osteoarthritis, which could significantly affect rehabilitation or complicate the assessment of PFPS.
• Individuals with severe knee osteoarthritis (e.g., Kellgren-Lawrence grade 3 or 4) as it may impact the treatment response and differ from the typical PFPS rehabilitation approach.
• Individuals with neurological conditions (e.g., stroke, multiple sclerosis or peripheral neuropathy) that affect movement, balance or cognition making participation in rehabilitation exercises unsafe or difficult.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Patellar Grind Test	12 Months	The Patellar Grind Test, also known as Clarke's Sign, is a physical examination used to assess patellofemoral joint pain, involving compression of the patella while the patient contracts their quadriceps, with a positive test indicated by pain or grinding
Numeric Pain Rating Scale (NPRS)	12 Months	Knee Pain during Daily Activities and Exercises is assessed using the numeric pain rating scale for Pain. It is highly reliable based on construct validity and it really measures the degrees of pain and possess significant test-retest reliability.; The lowest value, 0, means that the patient felt no pain at all. The highest value 10, means the worse pain that could be conceived.
Kujala Patellofemoral Score (Anterior Knee Pain Scale)	12 Months	Kujala Patellofemoral Score better known as Anterior Knee Pain Scale is self-administered questioner aimed at quantifying the severity of AKP and restriction in activity related to PFPS. It has 13 questions which are focused on certain activity or symptom.; Scoring: Each question is scored, and the total ranges from 0 to 100: 0: Higher severity of the symptoms and higher degree of self-implemented limitations.; 100: No symptoms, normal function. Interpretation of Scores. 85-100: Perfect working, few indications. 70-84: Good function, mild symptoms. 50-69: Sufficient function, phenomena slightly manifesting themselves. Below 50: Low, worst.

Trial Locations

Locations (1)

Superior University CRC; 🇵🇰 Lahore, Punjab, Pakistan