Treatments for Benign Paroxysmal Positional Vertigo (BPPV)

Phase 2

Completed

• Conditions: Vertigo
• Interventions: Behavioral: Canalith repositioning maneuver (Epley maneuver); Behavioral: Vestibular habituation exercises; Behavioral: ShamManeuver; Behavioral: Semont maneuver; Behavioral: Brandt-Daroff exercises

• Registration Number: NCT00000359
• Lead Sponsor: Baylor College of Medicine

Brief Summary

The purpose of this study was to determine the relative short- and long-term efficacy of several physical treatment paradigms commonly employed for the treatment of benign paroxysmal positional vertigo (BPPV), including the canalith repositioning (Epley) maneuver, the liberatory (Semont) maneuver, the Brandt-Daroff exercises and nonspecific vestibular habituation exercises. These procedures involve exercises and head manipulations. Vertigo intensity and frequency, the presence/absence of slow-phase eye movements, the degree of dizziness handicap and acts of daily living (ADL) were assessed. The study also ascertained the effects of co-morbid conditions on the response to treatment. While BPPV is a common and significant public health problem that has been recognized for several decades, this is the first systematic study of the relative treatment efficacy of different physical treatment modalities for this disorder.

Detailed Description

Not available

Study Timeline

• Study Start: 1998-10
• Study First Submitted: 1999-11-02
• Study First Submitted QC: 1999-11-02
• Study First Posted: 1999-11-03
• Primary Completion: 2003-06
• Study Completion: 2003-06
• Status Verified: 2012-07
• Last Update Submitted: 2012-07-25
• Last Update Posted: 2012-07-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Patients may be eligible for this study if they:

• Are at least 21 years old.
• Have a diagnosis of unilateral posterior semicircular canal BPPV according to established clinical test criteria.
• Have functional to normal range of motion of the neck and the back.

Exclusion Criteria

Patients will not be eligible for this study if they:

• Have a history of prior ear surgery or prior treatment for BPPV.
• Have an orthopedic or connective tissue disorder that impairs functional neck or trunk range of motion.
• Have a significant neurological disorder or spinal cord damage.
• Are on vestibular suppressant medications.
• Have Meniere's disease or acoustic neuromas.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Canalith repositioning maneuver	Canalith repositioning maneuver (Epley maneuver)	Repositioning treatment for posterior canal BPPV
Modified Epley maneuver	Vestibular habituation exercises	-
Sham	ShamManeuver	The subject sat in a chair; the head was passively tilted downward, turned away from the involved side, turned back to center, upward, away from the involved side, twice, slowly.
Liberatory maneuver	Semont maneuver	The standard liberatory maneuver (also known as the Semont maneuver) was used.
Brandt Daroff exercise	Brandt-Daroff exercises	Modified Brandt Daroff exercise performed as a self-liberatory exercise.

Primary Outcome Measures

Name	Time	Method
Vertigo	6 month s

Secondary Outcome Measures

Name	Time	Method
Balance	6 months

Trial Locations

Locations (1)

Baylor College of Medicine; 🇺🇸 Houston, Texas, United States