ISRCTN41579277已完成未知
Effect of a diet low in fructose and sucrose on insulin resistance: clinical trial in primary care
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 438
研究概览
简要总结
2017 protocol in https://www.ncbi.nlm.nih.gov/pubmed/28784181 2020 results in https://www.ncbi.nlm.nih.gov/pubmed/32325919 (added 06/05/2020)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Age between 29-66 years
- •2. BMI between 29 and 40.99 kg/m2
排除标准
- •1. Pregnancy (female participants only)
- •2. Behavioral eating disorders
- •3. Relevant gastrointestinal disease (ulcerating colitis, Crohn’s disease, celiac disease, digestive tract cancer)
- •4. Excessive alcohol consumption (>28 U or 280 g/week in men, > 17 U or 168 g/week in women
- •5. Severe cardiovascular disease
- •6. Diabetes,
- •7. Polycystic ovary disease
- •8. Treatment with any medication that could alter insulin sensitivity or body weight (corticosteroids, antipsychotics, antidepressants)
- •9. Pharmacological treatment for clinical or subclinical hypothyroidism
- •10. Hyperthyroidism
- •11. Depression
- •12. Psychosis
- •13. Microalbumin/creatinine ratio >100 mg/g or stage IIIB or higher chronic kidney disease (glomerular filtration rate < 45 mL/min)
- •14. Use of medication requiring frequent dose adjustments
- •15. Low intellectual or mental functioning that could interfere with the participant’s compliance with the recommendations
- •16. If the result of the glucose overload test is blood glucose = 200 mg/dL the participant is excluded if the physician opts to add medication or insulin to the dietary and physical exercise regime.
研究者
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