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Site-oriented depigmentation in vitiligo patients using Q-switched Nd:YAG laser (1064/532nm), cryotherapy and chemical peels: A comparative study.

Phase 4
Conditions
Skin and Connective Tissue Diseases
Registration Number
PACTR201811835577312
Lead Sponsor
Sarah Ibrahim
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
80
Inclusion Criteria

Patients older than 12 years
having either vitiligo universalis that left behind residual normally pigmented and cosmetically unacceptable areas over face, neck and/or upper limbs, or vitiligo vulgaris recalcitrant to treatment and interfering with patients’ social acceptance were included.

Exclusion Criteria

?Active cutaneous infection or inflammatory dermatoses.
?Uncooperative patients.
?Unrealistic expectations.
?History of abnormal scarring.
?Patients having cardiac or renal problems.
?Patients with impaired sensation or circulation, or abnormal reactions to cold (Raynaud's phenomenon and cold urticaria).

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The used depigmenting modalities proved to be effective in depigmentation of the remaining pigmented areas in vitiligo cases
Secondary Outcome Measures
NameTimeMethod
TCA peels are tolerable, cheap and available depigmenting agents in face and/ or neck depigmentation. QsNdYAG, cyotherapy and phenol 88 gave comparable results in upper limb depigmentation.
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