Glucose Control in Open Heart Surgery
Phase 1
Completed
- Conditions
- Hyperglycaemia During Perioperative PeriodHeart Valve DiseasesVentricular Dysfunction
- Registration Number
- NCT00370643
- Lead Sponsor
- University of Sao Paulo
- Brief Summary
The purpose of the study is to seek if there is difference to state glucose level in 80-120mg/dl or 200mg/dl in patients submitted to open heart surgery
- Detailed Description
Hyperglycaemia in the intensive care unit and perioperative period has been accused to be one of the causes of worse clinical outcome. It is known that in open heart surgeries the glucose level must be set less than 200mg/dl, but new trials had set the glucose level lower than that: 140mg/dl in some studies and even lower (80-110mg/dl). Our trial had the intention to seek if there is difference setting glucose level in 2 different ones would modifies clinical outcome.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 98
Inclusion Criteria
- adult more than 21 years old
- open heart surgery with cardiopulmonary bypass
Exclusion Criteria
- renal dysfunction
- reoperation
- use of inotropic support
- neurological dysfunction
- chronic pulmonary obstructive disease
- emergency or urgency
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Duration of intubation ICU length Blood transfusion Infection rate Renal dysfunction Neurological dysfunction Hospital length Mortality
- Secondary Outcome Measures
Name Time Method Length of surgery Length of cardiopulmonary bypass Parsonnet Canadian Multicenter index Physical status EuroSCORE
Trial Locations
- Locations (1)
Heart Institute, Hospital of Clinics, São Paulo University Medical School
🇧🇷São Paulo, Brazil