Efficacy of a Stepped Internet-based Program for Prevention and Early Intervention of Depression in Adolescents
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Depressive Symptoms
- Sponsor
- University of Chile
- Enrollment
- 947
- Locations
- 1
- Primary Endpoint
- Depressive Symptoms
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
Background: Depression is prevalent and can have devastating effects on the life of adolescents. Computerized intervention programs for depression have shown positive results. There is less evidence in prevention and early treatment for depression in Latin American adolescents.
Purpose: The purpose of this study is to determine whether a stepped internet-based program is effective to prevent and early intervene depression in adolescents attending 9th to 11th grade in eight schools in Santiago, Chile.
Study design: A two-arm cluster-randomized clinical trial will be carried out with approximately 600 adolescents.
Investigators
Vania Martínez-Nahuel
Principal Investigator
University of Chile
Eligibility Criteria
Inclusion Criteria
- •Attending from ninth grade to eleventh grade in the eight participating schools.
- •Informed consent and informed assent.
- •Score in the depression questionnaire PHQ-9 adolescent version between 5 and 14.
Exclusion Criteria
- •High suicide risk defined by score in question 9 of the PHQ-9 adolescent version of 2 or more.
- •Current treatment with antidepressant drugs.
- •Current treatment with psychotherapy.
Outcomes
Primary Outcomes
Depressive Symptoms
Time Frame: 6 months after baseline assessment
Patient Health Questionnaire-9 (PHQ-9) adolescent version, total score varies between 0 and 27, higher values represent a worse outcome
Secondary Outcomes
- Health-Related Quality of Life Index(6 and 12 months after baseline assessment)
- Depressive Symptoms(12 months after baseline assessment)
- Anxiety Symptoms(6 and 12 months after baseline assessment)
- Social Problem Solving Skills(6 and 12 months after baseline assessment)
- Dysfunctional Thoughts(6 and 12 months after baseline assessment)
- Emotion Regulation(6 and 12 months after baseline assessment)
- Depression Stigma(6 and 12 months after baseline assessment)