Circulating Hsp70 Levels and the Immunophenotype ofPeripheral Blood Lymphocytes as Potential Biomarkers forpatients with HNSCC

• Conditions: C76.0; K12.28; Head, face and neck

• Registration Number: DRKS00033819
• Lead Sponsor: Klinikum rechts der Isar, Klinik und Poliklinik für Mund-, Kiefer und Gesichtschirurgie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-03-06
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 650

Inclusion Criteria

All patients with primary squamous cell carcinoma or other tumor entities and abscesses who underwent surgery/therapy in the Department of Oral and Maxillofacial Surgery at the Technical University of Munich as well as healthy volunteers who signed the informed consent to study participation.

Exclusion Criteria

- Patients without tumor disease or abscesses
- Patients with external tumor aftercare

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Determination of potential biomarkers:<br>Determination of circulating Hsp70, SCCA, CEA, CTCs and immunophenotyping of lymphocytes in patients with head and neck cancer, in patients with abscesses and in healthy individuals until February 2027

Secondary Outcome Measures

Name	Time	Method
Recording of general patient data and forms of therapy