Ketamine for reducing suicidial thoughts in psychiatric disorders.
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To study the effectiveness of subanaesthetic doses of IV Ketamine in reducing suicidal ideation.
研究概览
简要总结
Emergency department visits for suicidal ideation or behavior have been increasing in all age groups, particularly young adults. In 1964 first tested in humans, in 1970 approved for use in united states. In 1990 found to have mood enhancing properties. In 2000 first controlled study for MDD. MDD do not experience remission with psychotherapy and antidepressants. ketamine appears to be one of the few effective treatment modalities for treatment resistant depression and acute suicidality. With severe unmet needs in bipolar depression, short term ketamine uses in bipolar depression as an add on treatment may be a promising option for severity abatement and social incapacity duration.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Those who are coming to psychiatric and emergency department with ideas of suicide and attempt of suicide.
排除标准
- •prior cardaic/respiratory/neurological abnormalities any abnormalities in basic investigations.
结局指标
主要结局
To study the effectiveness of subanaesthetic doses of IV Ketamine in reducing suicidal ideation.
时间窗: To study the effectiveness of subanaesthetic doses of IV Ketamine in reducing suicidial | ideation. HAM-D, HAM-A MADRS, MSSI after every session.
次要结局
- 1.Number of ketamine sessions required to reduce suicidal ideation.(2..Assess the functional outcome in patients receiving ketamine treatment using Global Assessment Functioning Scale.)
研究者
PEDDESUGARI HARIKA
NRI Academy of Sciences