Clinical Characteristics and Outcomes Among STEMI Patients with Cardiogenic Shock At Abu Dhabi City

Recruiting

• Conditions: ST Elevation Myocardial Infarction; Cardiogenic Shock

• Registration Number: NCT06535503
• Lead Sponsor: Abu Dhabi Health Services Company

Brief Summary

A retrospective study on the clinical characteristics and treatment outcomes of patients admitted with ST-elevation Myocardial Infarction (STEMI) complicated with cardiogenic shock (CS) during admission or CS development during their hospital stay for two tertiary hospitals in Abu Dhabi, UAE, from 2020-2024.

Detailed Description

Cardiovascular disease (CVD) accounts for 40% of mortality in the UAE, which is higher than the global average. Long-term trends, incidence studies, and best practice guidance on Cardiogenic Shock (CS) with ST-elevation Myocardial infarction (STEMI) in the United Arab Emirates (UAE) and the Gulf Cooperation Council (GCC) are limited.

Through this retrospective study, investigators aim to identify treatment modalities and trends, hospitalization events, and patient demographics and comorbidities which lead to participant recovery or mortality in Sheikh Khalifa Medical City (SKMC) and Sheikh Shakhbout Medical City (SSMC) tertiary hospitals for patients admitted with STEMI and CS or developed CS after hospitalization with STEMI during January 2020-January 2024.\[200-400 participants\]. Data will be collected from eligible patients' electronic medical records (EMR).

Study Timeline

• Study First Submitted: 2024-05-13
• Study Start: 2024-07-01
• Study First Submitted QC: 2024-07-30
• Study First Posted: 2024-08-02
• Primary Completion: 2025-01-01
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-13
• Last Update Posted: 2025-02-17
• Study Completion: 2025-05-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

• Age more than 18.
• STEMI complicated by cardiogenic shock.
• Were hospitalized or treated at SSMC or SKMC for STEMI complicated by cardiogenic shock.
• Patient admitted between January 2019 to March 2024.

Exclusion Criteria

• Age less than 18.
• Shock patient not related to Myocardial infarction.
• NSTEMI-related cardiogenic shock.
• Patients who were not treated at SSMC or SKMC for the STEMI complicated by cardiogenic shock.
• Patient not admitted between January 2019 to March 2024.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of CS-complicated AMI events	5 years	The incidence of CS-complicated AMI events will show an increase over the years because of advanced diagnostic modalities and a clearer definition of CS.
Analyze STEMI patient with CS disease profile	5 years	Incidence of Morbidity
Analyze treatment outcomes in the targeted population as per the patient profile	5 years	Incidence of Mortality
Analyze treatment outcomes	5 years	% of patients who were discharged

Trial Locations

Locations (2)

Sheikh Khalifa Medical City (SKMC); 🇦🇪 Abu Dhabi, United Arab Emirates

Sheikh Shakhbout Medical City (SKMC); 🇦🇪 Abu Dhabi, United Arab Emirates