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临床试验/NCT01046175
NCT01046175撤回2 期

Effect of Two Different Air-stacking Techniques, Combined With Manually Assisted Cough, on Peak Cough Flow (PCF) in Patients With Acute Cervical or High Thoracic Spinal Cord Injury

Ullevaal University Hospital2 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2010年2月1日最近更新:
适应症

试验速览

阶段
2 期
状态
撤回
发起方
入组人数
10
试验地点
2
主要终点
Peak cough flow (PCF)

研究概览

简要总结

Respiratory complications continue to be one of the leading causes of morbidity and mortality in people with spinal cord injury, especially among cervical and higher thoracic injuries. Both inspiratory and expiratory function are often severely decreased, leading to respiratory complications, such as atelectasis, pneumonia and ventilatory failure. The prevention of these respiratory complications needs to begin immediately after injury. To achieve effective expelling of secretions before they form mucus plugs, it is essential to improve patients ability to cough. Manually assisting the cough is one way of increasing cough flow, but an effective cough also requires adequate lung volumes. The emphasis should therefore be on expansion of the lungs before coughing. One way of expanding the lungs is by air-stacking. In air-stacking insufflations are stacked in the lungs to maximally expand them. Cough can be valued by measuring Peak Cough Flow (PCF). By combining air-stacking with manually assisted cough the PCF can be increased sufficiently. The aim of this study is to compare the effect of two different air-stacking techniques on PCF, air-stacking on a respirator versus air-stacking with a manual resuscitator.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • acute cervical or high thoracic spinal cord injury admitted to the ICU

排除标准

  • substantial abdominal or thoracic injury
  • substantial brain damage
  • intubated or tracheostomized patients
  • not able to cooperate
  • pregnant women

结局指标

主要结局

Peak cough flow (PCF)

时间窗: 2 weeks

次要结局

  • Patient preference of air-stacking technique(2 weeks)
  • Physiotherapist preference of air-stacking technique(2 weeks)

研究者

发起方
Ullevaal University Hospital
申办方类型
Other

研究点 (2)

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