US-Guided ESPB Versus TPVB on Acute and Chronic Pain After VATS

Not Applicable

Completed

• Conditions: Postoperative Pain; Acute Pain; Chronic Pain; Erector Spinae Plane Block; Video-Assisted Thoracoscopic Surgery; Thoracic Paravertebral Block
• Interventions: Procedure: Thoracic paravertebral block vs Erector spinae plane block

• Registration Number: NCT04964401
• Lead Sponsor: Atatürk Chest Diseases and Chest Surgery Training and Research Hospital

Brief Summary

Postoperative acute and chronic pain is frequently observed in patients undergoing video assisted thoracoscopic surgery (VATS). This prolongs the discharge time of patients and increases the frequency of postoperative pulmonary complications. Recently, alternative analgesic methods such as thoracic paravertebral block (TPVB) and erector spinae plane block (ESPB), which are thought to have less side effects than thoracic epidural analgesia, have been used. Among these methods, ultrasound (US) guided TPVB is the most preferred method. In addition, ESPB application is increasing in patients undergoing VATS. In the literature, the number of cases performed with ESPB and randomized controlled prospective studies with ESPB are increasing. In this study, it is planned to compare the effects of US-guided TPVB and ESPB on postoperative acute and chronic pain in patients undergoing VATS.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-04-13
• Study First Submitted: 2021-07-13
• Study First Submitted QC: 2021-07-13
• Study First Posted: 2021-07-16
• Status Verified: 2021-09
• Primary Completion: 2021-09-13
• Last Update Submitted: 2021-09-22
• Study Completion: 2021-09-23
• Last Update Posted: 2021-09-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Age between 18 and 80 years
• American Society of Anesthesiologists physical status I-II-III
• Body mass index between 18-30 kg/m2
• Patients undergoing elective video assiste thoracoscopic surgery

Exclusion Criteria

• Advanced cancer
• History of chronic analgesic therapy
• History of local anesthetic allergy
• Infection in the intervention area
• Patients with bleeding disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Erector spinae plane block	Thoracic paravertebral block vs Erector spinae plane block	After the linear ultrasound (US) probe will be placed 2-3 cm lateral to the T5 spinous process, 20 ml of 0.25% bupivacaine hydrochloride will be injected into the interfacial space below the erector spinae muscle, above the transverse process.
Thoracic Paravertebral Block	Thoracic paravertebral block vs Erector spinae plane block	After the linear ultrasound (US) probe will be placed 2-3 cm lateral to the thoracic 5 spinous process, the US-compatible needle will be advanced to the paravertebral area with in-plane technique, and 20 ml of 0.25% bupivacaine hydrochloride will be injected into this area.

Primary Outcome Measures

Name	Time	Method
Pain scores	24 hours after surgery	Pain will be assessed at rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Pain assessment will be done at 1st, 2nd, 4th, 8th, 16th and 24th hours after surgery.

Secondary Outcome Measures

Name	Time	Method
Chronic pain	First and 3th month	Chronic pain findings will be evaluated in the 1st month and 3rd month after surgery by using visual analog from 0 (no pain) to 10 (worst pain). Neuropathic pain symptoms (Burning, stabbing, or electric shock-like pain; tingling, numbness, or a "pins and needles" feeling, hyperalgesia, allodynia and hypoesthesia) will also be asked to the participants in the 1st month and 3rd month after surgery.

Trial Locations

Locations (1)

Ankara Atatürk Chest Disease and Chest Surgery Training and Research Hospital; 🇹🇷 Kecioren, Ankara, Turkey