Vascular Function in Adolescent, Diabetic Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 85
- 试验地点
- 2
- 主要终点
- Vascular abnormalities as measured by the SyphmgnoCor equipment
研究概览
简要总结
The objectives of this investigator initiated study are to:
- Determine if and when vascular abnormalities occur during early adolescence
- Determine if poor diabetic control is related to vascular abnormalities.
The development of vascular plaques and vascular contractility will be assessed through the use of the SyphmgnoCor equipment.
详细描述
Up to 85 Type 1 diabetic and healthy controls, 12-14 years of age, will be recruited for the study. Once the Permission/Assent form has been completed, a cuff will be applied to the arm and the pressure tonometer will be used on various vessels. Cardiovascular data will be recorded. The procedure is non-invasive, will last approximately 10 minutes and will be performed during a routine clinic visit. Onset of diabetes and level of diabetic control as measured by the most recent Hbg A1c (relative to the study visit) will be obtained from the medical record. Microalbumin levels covering the prior 12 months will be collected from the medical record of diabetic subjects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 12 Years 至 14 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Boys and girls ages 12-14 years who have Type 1 diabetes or are healthy controls
排除标准
- •Children and adolescents who do not meet inclusion criteria
结局指标
主要结局
Vascular abnormalities as measured by the SyphmgnoCor equipment
时间窗: End of study
次要结局
未报告次要终点