ICSI Outcome of Ejaculated Versus Extracted Testicular Spermatozoa

Completed

• Conditions: Intracytoplasmic Sperm Injection
• Interventions: Procedure: Intracytoplasmic sperm injection

• Registration Number: NCT03033563
• Lead Sponsor: Adam International Hospital

Brief Summary

The study is retrospective to compare ICSI outcome of patients with cryptozoospermia or severe oligozoospermia after use of ejaculated versus extracted testicular sperms in different cycles for the same patient.

Detailed Description

The study was carried out on couples who underwent ICSI in period 2012-2014 for male factor infertility.Patients with semen showing cryptozoospermia were candidates for inclusion in this study.

First cycle was done as ICSI with priority to ejaculated sperm; testicular sperm was used if no motile sperm was available. For failed cases a second cycle was repeated using either testicular sperm or ejaculated sperm.

Keywords:Cryptozoospermia, ejaculated spermatozoa, testicular spermatozoa, ICSI.

Study Timeline

• Study Start: 2012-01-01
• Primary Completion: 2014-12-01
• Study Completion: 2014-12-31
• Status Verified: 2017-01
• Study First Submitted: 2017-01-21
• Study First Submitted QC: 2017-01-24
• Last Update Submitted: 2017-01-24
• Study First Posted: 2017-01-27
• Last Update Posted: 2017-01-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 430

Inclusion Criteria

• Couples seeking ICSI.

Exclusion Criteria

• Couples not seeking ICSI.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Testicular tissue versus ejaculate	Intracytoplasmic sperm injection	Evaluation of ICSI outcome.

Primary Outcome Measures

Name	Time	Method
Intracytoplasmic sperm injection outcome	three years	Pregnancy rate.