Preliminary Study on the Diagnostic Value Comparison of 18F-FAPI-04 PET/CT and PET/MR in Gastric Cancer
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- 18F-FAPI-04 PET imaging diagnosis of gastric cancer detection rate
研究概览
简要总结
This project aims to comprehensively analyze the diagnostic efficacy of SUVmax, SUVean, TLG, MTV, etc. in gastric cancer through 18F-FAPI-04 PET/CT imaging combined with serum tumor markers and other methods, and construct a molecular imaging diagnostic model for gastric cancer; Next, analyze the diagnostic efficacy of 18F-FAPI-04 PET/CT and PET/MR multimodal imaging in evaluating SUVmax, PET/CT-PCI, and PET/MR-PCI for gastric cancer peritoneal metastasis, and construct a molecular imaging diagnostic model for gastric cancer peritoneal metastasis; Exploring the clinical value of 18F-FAPI-04 PET/CT and PET/MR imaging in the diagnosis and staging of gastric cancer.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age over 18 years old;
- •Diagnosed as a patient with gastric cancer;
- •Receive FAPI PET/CT and FDG PET/CT imaging within one week;
- •Perform serum tumor marker testing one week before and after scanning
排除标准
- •History of other malignant tumors;
- •Patients with severe infections, severe underlying diseases such as heart, kidney, and liver;
- •Patients with contraindications for PET-CT examination, poor physical condition, and inability to tolerate the examination;
- •Patients with unorganized pathology or incomplete clinical data
结局指标
主要结局
18F-FAPI-04 PET imaging diagnosis of gastric cancer detection rate
时间窗: 2 years
Exploring the feasibility of using targeted fibroblast activation protein (FAP) PET/CT imaging for gastric cancer; Compare the advantages and disadvantages of 18F-FAPI-04 and 18F-FDG in gastric cancer imaging, explore the clinical application value of 18F-FAPI-04 PET/CT in gastric cancer imaging, and construct a molecular imaging diagnostic model for gastric cancer
次要结局
- Detection rate of peritoneal metastasis in gastric cancer(2 years)
研究者
Hui Ye
Professor
Hunan Cancer Hospital