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临床试验/NCT04225637
NCT04225637
已完成
不适用

Comparison Between Two Activation Protocols of Miniscrew-Supported Maxillary Expander in Adolescents: A Randomized Controlled Clinical Trial

Alexandria University1 个研究点 分布在 1 个国家目标入组 30 人2019年3月1日

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Palatal Expansion Technique
发起方
Alexandria University
入组人数
30
试验地点
1
主要终点
Transverse skeletal changes from baseline to an average of 5 months after the initial activation, measured using cone beam computed tomography (CBCT)
状态
已完成
最后更新
4年前

概览

简要总结

Miniscrew-supported maxillary expanders provide advantages over conventional tooth-supported expanders. However, there is no consensus in the literature regarding their activation protocol. The purpose of the clinical trial is to evaluate and compare the effects of slow and rapid activation rates of miniscrew-supported expanders on the skeletal changes, dento-alveolar changes and the pain experience.

详细描述

Transverse maxillary deficiency is one of the problems that are commonly encountered in the orthodontic practice. Miniscrew-supported maxillary expansion represents a promising modality for the treatment of transverse maxillary deficiency. However, controversies still exist regarding the activation protocol. One of these controversies is whether using a slow activation protocol would be more beneficial to the patients compared to a rapid activation protocol. Another question that consequently ensues is whether such activation protocol would result in less pain compared to the rapid activation protocol. The null hypothesis of the current study is that there is no difference between slow and rapid activation protocols of miniscrew-supported expander.

注册库
clinicaltrials.gov
开始日期
2019年3月1日
结束日期
2021年6月1日
最后更新
4年前
研究类型
Interventional
研究设计
Parallel
性别
All

研究者

责任方
Principal Investigator
主要研究者

Yomna Mohamed Mohamed Yacout

Assistant lecturer

Alexandria University

入排标准

入选标准

  • Permanent dentition.
  • Participants indicated for skeletal maxillary expansion due to unilateral or bilateral posterior cross bite or maxillary transverse deficiency
  • Good oral hygiene

排除标准

  • History of previous orthodontic or orthopedic treatment
  • History of maxillary trauma
  • Patients with congenital craniofacial malformations
  • Patients receiving pharmacological agents or having systemic diseases that might affect the bone metabolism or the pain response

结局指标

主要结局

Transverse skeletal changes from baseline to an average of 5 months after the initial activation, measured using cone beam computed tomography (CBCT)

时间窗: At baseline and an average of 5 months after the initial activation

The data from CBCT scans at the different time points will be exported in Digital Imaging and Communications in Medicine (DICOM) format and processed using suitable software. The relevant landmarks will be defined and located by the investigator to measure the transverse skeletal changes in mm from baseline to the end of passive retention of the expansion.

Dento-alveolar inclination changes from baseline to an average of 5 months after the initial activation, measured using CBCT

时间窗: At baseline and an average of 5 months after the initial activation

The data from CBCT scans at the different time points will be exported in DICOM format and processed using suitable software. The relevant landmarks will be defined and located by the investigator to measure the changes in dento-alveolar inclination from baseline to the end of passive retention of the expansion.

次要结局

  • Pain score on NRS after the first activation of the maxillary expander(On day 1 after the first activation of the maxillary expander)
  • Pain score on Numeric Rating Scale (NRS) at baseline(Baseline)
  • Pain score on NRS after 1 week of activation of the maxillary expander(After 1 week of activation of the maxillary expander)
  • Pain score on NRS after the last activation of the maxillary expander(At the end of active expansion (an estimated average of 2 to 3 weeks in the rapid expansion group, and 7 to 12 weeks in the slow expansion group))

研究点 (1)

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